UniProt Q9UKX7
Nuclear pore complex protein Nup50 (Q9UKX7)
Nuclear pore complex protein Nup50 (UniProt Q9UKX7): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UKX7
- Protein
- Nuclear pore complex protein Nup50
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
7 records of Q9UKX7 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EC1 | Solution structure of the RanBD1 domain from human Nucleoporin 50 kDa | solution nmr | A | — | — |
| 2EC1 | Solution structure of the RANBD1 domain from human nucleoporin 50 kda | solution nmr | A | — | — |
| 3TJ3 | Structure of importin a5 bound to the N-terminus of Nup50 | x-ray diffraction | C, D | — | — |
| 3TJ3 | Structure of importin A5 bound to the N-terminus of NUP50 | x-ray diffraction | C, D | — | — |
| 7MO0 | Crystal Structure of Nucleoporin NUP50 Ran-Binding Domain in Complex with Ran-GPPNHP | x-ray diffraction | B, D | SO4 | 5 (best 0.75) |
| 7MO0 | Crystal structure of nucleoporin NUP50 ran-binding domain in complex with ran-gppnhp | x-ray diffraction | B, D | SO4 | — |
| Q9UKX7 | AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP50 (Q9UKX7) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 7MO0 chain D against the predicted model Q9UKX7: TM-score 0.94, RMSD 1.22 Å
- 7MO0 chain D against the predicted model Q9UKX7: TM-score 0.94, RMSD 1.22 Å
- 7MO0 chain B against the predicted model Q9UKX7: TM-score 0.93, RMSD 1.24 Å
- 7MO0 chain B against the predicted model Q9UKX7: TM-score 0.93, RMSD 1.24 Å
- 2EC1 chain A against the predicted model Q9UKX7: TM-score 0.92, RMSD 0.98 Å
- 2EC1 chain A against the predicted model Q9UKX7: TM-score 0.92, RMSD 0.98 Å
- 3TJ3 chain C against the predicted model Q9UKX7: TM-score 0.43, RMSD 2.97 Å
- 3TJ3 chain C against the predicted model Q9UKX7: TM-score 0.43, RMSD 2.97 Å
- 3TJ3 chain D against the predicted model Q9UKX7: TM-score 0.43, RMSD 2.92 Å
- 3TJ3 chain D against the predicted model Q9UKX7: TM-score 0.43, RMSD 2.92 Å
Elsewhere
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