UniProt Q9UKT5
F-box only protein 4 (Q9UKT5)
F-box only protein 4 (UniProt Q9UKT5): 5 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UKT5
- Protein
- F-box only protein 4
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
6 records of Q9UKT5 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3L2O | Structure-Based Mechanism of Dimerization-Dependent Ubiquitination by the SCFFbx4 Ubiquitin Ligase | x-ray diffraction | B | — | — |
| 3L2O | Structure-based mechanism of dimerization-dependent ubiquitination by the SCFFBX4 ubiquitin ligase | x-ray diffraction | B | — | — |
| 3L82 | X-ray Crystal structure of TRF1 and Fbx4 complex | x-ray diffraction | B | — | — |
| 3L82 | X-ray crystal structure of TRF1 and FBX4 complex | x-ray diffraction | B | — | — |
| 9JKB | Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO4 SCF ubiquition ligase complex | electron microscopy | C, D | — | 7 (best 0.76) |
| Q9UKT5 | AlphaFold monomer V2.0 prediction for F-box only protein 4 (Q9UKT5) | predicted | A | — | — |
Experiment against prediction
- 3L82 chain B against the predicted model Q9UKT5: TM-score 0.95, RMSD 1.45 Å
- 3L82 chain B against the predicted model Q9UKT5: TM-score 0.95, RMSD 1.45 Å
- 9JKB chain C against the predicted model Q9UKT5: TM-score 0.91, RMSD 1.82 Å
- 9JKB chain D against the predicted model Q9UKT5: TM-score 0.75, RMSD 2.13 Å
- 3L2O chain B against the predicted model Q9UKT5: TM-score 0.66, RMSD 1.52 Å
- 3L2O chain B against the predicted model Q9UKT5: TM-score 0.66, RMSD 1.52 Å
Elsewhere
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