UniProt Q9UK73
Protein fem-1 homolog B (Q9UK73)
Protein fem-1 homolog B (UniProt Q9UK73): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UK73
- Protein
- Protein fem-1 homolog B
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 3 records with a druggable one
Structures
8 records of Q9UK73 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LBF | Crystal structure of FEM1B | x-ray diffraction | A, B | SO4 | — |
| 6LBF | Crystal structure of FEM1B | x-ray diffraction | A, B | SO4 | — |
| 7CNG | Structure of CDK5R1 bound FEM1B | — | — | — | |
| 7EL6 | Structure of SMCR8 bound FEM1B | x-ray diffraction | A, B | — | — |
| 8IJ1 | Protomer 1 and 2 of the asymmetry trimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complex | electron microscopy | D, I | ZN | 6 (best 0.64) |
| 8WQE | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1) | electron microscopy | D, B | — | 11 (best 0.76) |
| 8WQF | cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2) | electron microscopy | F, J | — | 8 (best 0.74) |
| Q9UK73 | AlphaFold monomer V2.0 prediction for protein fem-1 homolog B (Q9UK73) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8WQF chain F against the predicted model Q9UK73: TM-score 0.95, RMSD 1.50 Å
- 7EL6 chain B against the predicted model Q9UK73: TM-score 0.95, RMSD 1.59 Å
- 8WQF chain J against the predicted model Q9UK73: TM-score 0.94, RMSD 2.34 Å
- 7EL6 chain A against the predicted model Q9UK73: TM-score 0.94, RMSD 1.87 Å
- 8WQE chain B against the predicted model Q9UK73: TM-score 0.93, RMSD 2.48 Å
- 6LBF chain B against the predicted model Q9UK73: TM-score 0.93, RMSD 1.84 Å
- 6LBF chain B against the predicted model Q9UK73: TM-score 0.93, RMSD 1.84 Å
- 6LBF chain A against the predicted model Q9UK73: TM-score 0.92, RMSD 1.84 Å
- 6LBF chain A against the predicted model Q9UK73: TM-score 0.92, RMSD 1.84 Å
- 8WQE chain D against the predicted model Q9UK73: TM-score 0.92, RMSD 2.77 Å
Elsewhere
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