UniProt Q9UK45
U6 snRNA-associated Sm-like protein LSm7 (Q9UK45)
U6 snRNA-associated Sm-like protein LSm7 (UniProt Q9UK45): 22 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UK45
- Protein
- U6 snRNA-associated Sm-like protein LSm7
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
23 records of Q9UK45 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCR | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | electron microscopy | 7 | — | — |
| 3JCR | 3D structure determination of the HUMAN*U4/U6.U5* tri-snrnp complex | electron microscopy | 7 | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | t | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | t | — | — |
| 6AH0 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | electron microscopy | y | — | — |
| 6AH0 | The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex) | electron microscopy | y | — | — |
| 6AHD | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | electron microscopy | y | — | — |
| 6QW6 | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | electron microscopy | 67 | — | — |
| 6QX9 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | electron microscopy | 67 | — | — |
| 7ABG | Human pre-Bact-1 spliceosome | electron microscopy | A2 | — | — |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 6f | — | — |
| 8H6J | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | electron microscopy | 6f | — | — |
| 8H6K | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | electron microscopy | 6f | — | — |
| 8H6L | Cryo-EM structure of human exon-defined spliceosome in the early B state. | electron microscopy | 6f | — | — |
| 8QO9 | Cryo-EM structure of a human spliceosomal B complex protomer | electron microscopy | 67 | — | — |
| 8QXD | Cryo-EM structure of the cross-exon pre-B complex | electron microscopy | 67 | — | — |
| 8QZS | Cryo-EM structure of the cross-exon B-like complex | electron microscopy | 67 | — | — |
| 8R08 | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | electron microscopy | 67 | — | — |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | 67 | — | — |
| 8R0A | Cryo-EM structure of the cross-exon pre-B+5'ss complex | electron microscopy | 67 | — | — |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | 67 | — | — |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | 67 | — | — |
| Q9UK45 | AlphaFold monomer V2.0 prediction for U6 snrna-associated sm-like protein LSM7 (Q9UK45) | predicted | A | — | 1 (best 0.34) |
Experiment against prediction
- 6AH0 chain y against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 6AH0 chain y against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 8H6E chain 6f against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 8H6J chain 6f against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 6AHD chain y against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 8H6K chain 6f against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 8H6L chain 6f against the predicted model Q9UK45: TM-score 0.96, RMSD 0.57 Å
- 8QO9 chain 67 against the predicted model Q9UK45: TM-score 0.95, RMSD 0.65 Å
- 8QZS chain 67 against the predicted model Q9UK45: TM-score 0.94, RMSD 0.73 Å
- 7ABG chain A2 against the predicted model Q9UK45: TM-score 0.90, RMSD 1.25 Å
Elsewhere
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