UniProt Q9UK32
Ribosomal protein S6 kinase alpha-6 (Q9UK32)
Ribosomal protein S6 kinase alpha-6 (UniProt Q9UK32), EC 2.7.11.1: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UK32
- Protein
- Ribosomal protein S6 kinase alpha-6
- EC
- 2.7.11.1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 3 records with a druggable one
Structures
7 records of Q9UK32 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G76 | Phosphorylated RSK4 N-terminal Kinase Domain in complex with AMP-PNP | x-ray diffraction | A, B | ANP, ZN | 6 (best 0.65) |
| 6G76 | Phosphorylated RSK4 N-terminal kinase domain in complex with AMP-pnp | x-ray diffraction | A, B | ANP, ZN | — |
| 6G77 | RSK4 N-terminal Kinase Domain in complex with AMP-PNP | x-ray diffraction | A, B | ANP, ZN | 10 (best 0.66) |
| 6G77 | RSK4 N-terminal kinase domain in complex with AMP-pnp | x-ray diffraction | A, B | ANP, ZN | — |
| 6G78 | RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP | x-ray diffraction | A, B | ANP | 6 (best 0.66) |
| 6G78 | RSK4 N-terminal kinase domain S232E in complex with AMP-pnp | x-ray diffraction | A, B | ANP | — |
| Q9UK32 | AlphaFold monomer V2.0 prediction for ribosomal protein S6 kinase alpha-6 (Q9UK32) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6G78 chain B against the predicted model Q9UK32: TM-score 0.87, RMSD 2.48 Å
- 6G78 chain B against the predicted model Q9UK32: TM-score 0.87, RMSD 2.48 Å
- 6G76 chain B against the predicted model Q9UK32: TM-score 0.86, RMSD 2.50 Å
- 6G76 chain B against the predicted model Q9UK32: TM-score 0.86, RMSD 2.50 Å
- 6G78 chain A against the predicted model Q9UK32: TM-score 0.86, RMSD 2.57 Å
- 6G78 chain A against the predicted model Q9UK32: TM-score 0.86, RMSD 2.57 Å
- 6G77 chain B against the predicted model Q9UK32: TM-score 0.85, RMSD 2.48 Å
- 6G76 chain A against the predicted model Q9UK32: TM-score 0.85, RMSD 2.54 Å
- 6G76 chain A against the predicted model Q9UK32: TM-score 0.85, RMSD 2.54 Å
- 6G77 chain A against the predicted model Q9UK32: TM-score 0.85, RMSD 2.55 Å
Elsewhere
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