UniProt Q9UK05
Growth/differentiation factor 2 (Q9UK05)
Growth/differentiation factor 2 (UniProt Q9UK05): 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UK05
- Protein
- Growth/differentiation factor 2
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
17 records of Q9UK05 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZKZ | Crystal Structure of BMP9 | x-ray diffraction | A | — | — |
| 1ZKZ | Crystal structure of BMP9 | x-ray diffraction | A | — | — |
| 4FAO | Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex | x-ray diffraction | A, B, G, H, M, N, S, T, a, b, g, h | — | — |
| 4FAO | Specificity and structure of a high affinity activin-like 1 (ALK1) signaling complex | x-ray diffraction | A, B, G, H, M, N, S, T, a, b, g, h | — | — |
| 4MPL | Crystal structure of BMP9 at 1.90 Angstrom | x-ray diffraction | A | — | — |
| 4MPL | Crystal structure of BMP9 at 1.90 ångström | x-ray diffraction | A | — | — |
| 4YCG | Pro-bone morphogenetic protein 9 | x-ray diffraction | C, D | — | — |
| 4YCG | Pro-bone morphogenetic protein 9 | x-ray diffraction | C, D | — | — |
| 4YCI | non-latent pro-bone morphogenetic protein 9 | x-ray diffraction | C, D | — | — |
| 4YCI | Non-latent pro-bone morphogenetic protein 9 | x-ray diffraction | C, D | — | — |
| 5HZW | Crystal structure of the orphan region of human endoglin/CD105 in complex with BMP9 | x-ray diffraction | B | — | — |
| 5HZW | Crystal structure of the orphan region of human ENDOGLIN/CD105 in complex with BMP9 | x-ray diffraction | B | — | — |
| 5I05 | Crystal structure of human BMP9 at 1.87 A resolution | x-ray diffraction | A | — | — |
| 5I05 | Crystal structure of human BMP9 at 1.87 a resolution | x-ray diffraction | A | — | — |
| 6SF2 | Ternary complex of human bone morphogenetic protein 9 (BMP9) growth factor domain, its prodomain… | x-ray diffraction | B, C, E, F | NAG | 9 (best 0.71) |
| 6SF2 | Ternary complex of human bone morphogenetic protein 9 (BMP9) growth factor domain, its prodomain… | x-ray diffraction | B, C, E, F | NAG | — |
| Q9UK05 | AlphaFold monomer V2.0 prediction for GROWTH/DIFFERENTIATION factor 2 (Q9UK05) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 6SF2 chain E against the predicted model Q9UK05: TM-score 0.97, RMSD 0.72 Å
- 6SF2 chain E against the predicted model Q9UK05: TM-score 0.97, RMSD 0.72 Å
- 6SF2 chain B against the predicted model Q9UK05: TM-score 0.95, RMSD 0.87 Å
- 6SF2 chain B against the predicted model Q9UK05: TM-score 0.95, RMSD 0.87 Å
- 6SF2 chain F against the predicted model Q9UK05: TM-score 0.95, RMSD 1.39 Å
- 6SF2 chain F against the predicted model Q9UK05: TM-score 0.95, RMSD 1.39 Å
- 4YCG chain D against the predicted model Q9UK05: TM-score 0.94, RMSD 1.06 Å
- 4YCG chain D against the predicted model Q9UK05: TM-score 0.94, RMSD 1.06 Å
- 4FAO chain M against the predicted model Q9UK05: TM-score 0.93, RMSD 1.06 Å
- 4FAO chain M against the predicted model Q9UK05: TM-score 0.93, RMSD 1.06 Å
Elsewhere
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