UniProt Q9UJW3
DNA (cytosine-5)-methyltransferase 3-like (Q9UJW3)
DNA (cytosine-5)-methyltransferase 3-like (UniProt Q9UJW3): 36 experimental structures and 1 predicted model on GenesisL1, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UJW3
- Protein
- DNA (cytosine-5)-methyltransferase 3-like
- Experimental structures
- 36
- Predicted models
- 1
- Pockets
- 38 · 6 records with a druggable one
Structures
37 records of Q9UJW3 in the MolNFT archive: 36 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2PV0 | DNA methyltransferase 3 like protein (DNMT3L) | x-ray diffraction | B, A, C | — | — |
| 2PV0 | DNA methyltransferase 3 like protein (DNMT3L) | x-ray diffraction | B, A, C | — | — |
| 2PVC | DNMT3L recognizes unmethylated histone H3 lysine 4 | x-ray diffraction | B, A, C | — | — |
| 2PVC | DNMT3L recognizes unmethylated histone H3 lysine 4 | x-ray diffraction | B, A, C | — | — |
| 2QRV | Structure of Dnmt3a-Dnmt3L C-terminal domain complex | x-ray diffraction | B, C, F, G | — | — |
| 2QRV | Structure of DNMT3A-DNMT3L C-terminal domain complex | x-ray diffraction | B, C, F, G | — | — |
| 4U7P | Crystal structure of DNMT3A-DNMT3L complex | x-ray diffraction | B | — | — |
| 4U7P | Crystal structure of DNMT3A-DNMT3L complex | x-ray diffraction | B | — | — |
| 4U7T | Crystal structure of DNMT3A-DNMT3L in complex with histone H3 | x-ray diffraction | B, D | — | — |
| 4U7T | Crystal structure of DNMT3A-DNMT3L in complex with histone H3 | x-ray diffraction | B, D | — | — |
| 5YX2 | Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites | x-ray diffraction | B, C | — | 6 (best 0.62) |
| 5YX2 | Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two cpg sites | x-ray diffraction | B, C | — | — |
| 6BRR | Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two cpg sites | x-ray diffraction | B, C | — | — |
| 6F57 | Crystal structure of DNMT3A-DNMT3L in complex with single cpg- containing DNA | x-ray diffraction | B, C | — | — |
| 6KDA | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site | x-ray diffraction | B, C | — | — |
| 6KDA | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing cpgpg site | x-ray diffraction | B, C | — | — |
| 6KDB | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site | x-ray diffraction | B, C | — | — |
| 6KDB | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing cpgpt site | x-ray diffraction | B, C | — | — |
| 6KDL | Crystal structure of human DNMT3B-DNMT3L complex (I) | x-ray diffraction | B, C | — | — |
| 6KDP | Crystal structure of human DNMT3B-DNMT3L complex (II) | x-ray diffraction | B, C | — | — |
| 6KDT | Crystal structure of human DNMT3B (Q772R)-DNMT3L complex | x-ray diffraction | B, C | — | — |
| 6U8P | Crystal structure of DNMT3B-DNMT3L in complex with cpgpa DNA | x-ray diffraction | B, C | — | — |
| 6U8V | Crystal structure of DNMT3B-DNMT3L in complex with cpgpt DNA | x-ray diffraction | B, C | — | — |
| 6U8W | Crystal structure of DNMT3B(K777A)-DNMT3L in complex with CpGpT DNA | x-ray diffraction | B, C | — | 9 (best 0.71) |
| 6U8W | Crystal structure of DNMT3B(K777A)-DNMT3L in complex with cpgpt DNA | x-ray diffraction | B, C | — | — |
| 6U8X | Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA | x-ray diffraction | B, C | — | 6 (best 0.55) |
| 6U8X | Crystal structure of DNMT3B-DNMT3L in complex with cpapg DNA | x-ray diffraction | B, C | — | — |
| 6U90 | Crystal structure of DNMT3B(N779A)-DNMT3L in complex with cpgpt DNA | x-ray diffraction | B, C | — | — |
| 6U91 | Crystal structure of DNMT3B(Q772R)-DNMT3L in complex with cpgpt DNA | x-ray diffraction | B, C | — | — |
| 6W89 | Structure of DNMT3A (R882H) in complex with cga DNA | x-ray diffraction | B, C, H, I | — | — |
| 6W8B | Structure of DNMT3A in complex with CGA DNA | x-ray diffraction | B, C, I, J | — | 5 (best 0.79) |
| 6W8B | Structure of DNMT3A in complex with cga DNA | x-ray diffraction | B, C, I, J | — | — |
| 6W8D | Structure of DNMT3A (R882H) in complex with CGT DNA | x-ray diffraction | B, C | — | 8 (best 0.74) |
| 6W8D | Structure of DNMT3A (R882H) in complex with cgt DNA | x-ray diffraction | B, C | — | — |
| 6W8J | Structure of DNMT3A (R882H) in complex with cag DNA | x-ray diffraction | B, C | — | — |
| 8XEE | Human DNMT3B mutant-R823G | x-ray diffraction | B, C | — | 4 (best 0.66) |
| Q9UJW3 | AlphaFold monomer V2.0 prediction for DNA (cytosine-5)-methyltransferase 3-like (Q9UJW3) | predicted | A | — | — |
Experiment against prediction
- 6KDP chain B against the predicted model Q9UJW3: TM-score 0.98, RMSD 0.77 Å
- 2PV0 chain A against the predicted model Q9UJW3: TM-score 0.98, RMSD 1.03 Å
- 2PV0 chain A against the predicted model Q9UJW3: TM-score 0.98, RMSD 1.03 Å
- 6KDT chain C against the predicted model Q9UJW3: TM-score 0.98, RMSD 0.86 Å
- 6KDP chain C against the predicted model Q9UJW3: TM-score 0.98, RMSD 0.85 Å
- 2PVC chain A against the predicted model Q9UJW3: TM-score 0.98, RMSD 1.09 Å
- 2PVC chain A against the predicted model Q9UJW3: TM-score 0.98, RMSD 1.09 Å
- 6KDB chain B against the predicted model Q9UJW3: TM-score 0.97, RMSD 0.86 Å
- 6KDB chain B against the predicted model Q9UJW3: TM-score 0.97, RMSD 0.86 Å
- 2PVC chain C against the predicted model Q9UJW3: TM-score 0.97, RMSD 1.13 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.