UniProt Q9UJM3
ERBB receptor feedback inhibitor 1 (Q9UJM3)
ERBB receptor feedback inhibitor 1 (UniProt Q9UJM3): 14 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UJM3
- Protein
- ERBB receptor feedback inhibitor 1
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
15 records of Q9UJM3 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2RF9 | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | x-ray diffraction | C, D | — | — |
| 2RF9 | Crystal structure of the complex between the EGFR kinase domain and a MIG6 peptide | x-ray diffraction | C, D | — | — |
| 2RFD | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | x-ray diffraction | C, D | — | — |
| 2RFD | Crystal structure of the complex between the EGFR kinase domain and a MIG6 peptide | x-ray diffraction | C, D | — | — |
| 2RFE | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | x-ray diffraction | E, F | — | — |
| 2RFE | Crystal structure of the complex between the EGFR kinase domain and a MIG6 peptide | x-ray diffraction | E, F | — | — |
| 4I21 | Crystal structure of L858R + T790M EGFR kinase domain in complex with MIG6 peptide | x-ray diffraction | C, D | — | — |
| 4I21 | Crystal structure of L858R + T790M EGFR kinase domain in complex with MIG6 peptide | x-ray diffraction | C, D | — | — |
| 4R3P | Crystal structures of EGFR in complex with Mig6 | x-ray diffraction | B | — | — |
| 4R3P | Crystal structures of EGFR in complex with MIG6 | x-ray diffraction | B | — | — |
| 4R3R | Crystal structures of EGFR in complex with Mig6 | x-ray diffraction | B | — | — |
| 4R3R | Crystal structures of EGFR in complex with MIG6 | x-ray diffraction | B | — | — |
| 4ZJV | crystal structure of EGFR kinase domain in complex with Mitogen-inducible gene 6 protein | x-ray diffraction | C, D | — | 5 (best 0.73) |
| 4ZJV | Crystal structure of EGFR kinase domain in complex with mitogen- inducible gene 6 protein | x-ray diffraction | C, D | — | — |
| Q9UJM3 | AlphaFold monomer V2.0 prediction for erbb receptor feedback inhibitor 1 (Q9UJM3) | predicted | A | — | — |
Experiment against prediction
- 4ZJV chain D against the predicted model Q9UJM3: TM-score 0.93, RMSD 0.59 Å
- 4ZJV chain D against the predicted model Q9UJM3: TM-score 0.93, RMSD 0.59 Å
- 4ZJV chain C against the predicted model Q9UJM3: TM-score 0.92, RMSD 0.81 Å
- 4ZJV chain C against the predicted model Q9UJM3: TM-score 0.92, RMSD 0.81 Å
- 2RF9 chain C against the predicted model Q9UJM3: TM-score 0.83, RMSD 0.63 Å
- 2RF9 chain C against the predicted model Q9UJM3: TM-score 0.83, RMSD 0.63 Å
- 2RFE chain E against the predicted model Q9UJM3: TM-score 0.79, RMSD 0.65 Å
- 2RFE chain E against the predicted model Q9UJM3: TM-score 0.79, RMSD 0.65 Å
- 4I21 chain C against the predicted model Q9UJM3: TM-score 0.78, RMSD 0.96 Å
- 4I21 chain C against the predicted model Q9UJM3: TM-score 0.78, RMSD 0.96 Å
Elsewhere
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