UniProt Q9UHV7
Mediator of RNA polymerase II transcription subunit 13 (Q9UHV7)
Mediator of RNA polymerase II transcription subunit 13 (UniProt Q9UHV7): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 35 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UHV7
- Protein
- Mediator of RNA polymerase II transcription subunit 13
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 35 · 5 records with a druggable one
Structures
6 records of Q9UHV7 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8T9D | CryoEM structure of TR-TRAP | electron microscopy | 9 | — | — |
| 8TQ2 | Structure of the kinase lobe of human CDK8 kinase module | electron microscopy | D | — | 2 (best 0.65) |
| 8TQC | Structure of the human CDK8 kinase module | electron microscopy | D | ZN | 10 (best 0.85) |
| 8TQW | Structure of human transcriptional Mediator complex | electron microscopy | d | ZN | 2 (best 0.83) |
| 8TRH | The IDRc bound human core Mediator complex | electron microscopy | d | — | 1 (best 0.83) |
| Q9UHV7 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 13… | predicted | A | — | 20 (best 0.87) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 8TQC chain D against the predicted model Q9UHV7: TM-score 0.96, RMSD 2.39 Å
- 8TQW chain d against the predicted model Q9UHV7: TM-score 0.95, RMSD 2.45 Å
- 8TQ2 chain D against the predicted model Q9UHV7: TM-score 0.32, RMSD 2.31 Å
- 8TRH chain d against the predicted model Q9UHV7: TM-score 0.31, RMSD 3.55 Å
- 8T9D chain 9 against the predicted model Q9UHV7: TM-score 0.22, RMSD 2.96 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.