UniProt Q9UG07
Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b (Q9UG07)
Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b (UniProt Q9UG07): 7 experimental structures on GenesisL1, 5 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9UG07
- Protein
- Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b
- Experimental structures
- 7
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 5 · 0 records with a druggable one
Structures
7 records of Q9UG07 in the MolNFT archive: 7 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZBQ | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | x-ray diffraction | A, B | QE2 | 2 (best 0.30) |
| 6ZBQ | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A, B | QE2 | — |
| 6ZBZ | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A, B, C, D | QE5 | — |
| 6ZC3 | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A, B | JOR | — |
| 6ZC4 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | x-ray diffraction | A, B | QEZ | 3 (best 0.34) |
| 6ZC4 | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A, B | QEZ | — |
| 6ZC7 | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A, B | V31 | — |
Ligands
- QE2 · 5-fluoranyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid · in 2 records
- QEZ · 5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid · in 2 records
- JOR · 5-fluoranyl-2-(methylsulfonylamino)benzoic acid · in 1 record
- QE5 · 2-[(3,4-dimethylphenyl)sulfonylamino]-5-fluoranyl-benzoic acid · in 1 record
- V31 · 5-bromanyl-2-[(phenylmethyl)sulfonylamino]benzoic acid · in 1 record
Elsewhere
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