UniProt Q9UF56
F-box/LRR-repeat protein 17 (Q9UF56)
F-box/LRR-repeat protein 17 (UniProt Q9UF56): 5 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UF56
- Protein
- F-box/LRR-repeat protein 17
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 26 · 3 records with a druggable one
Structures
6 records of Q9UF56 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W66 | The structure of the F64A, S172A mutant KEAP1-btb domain in complex with SKP1-FBXL17 | x-ray diffraction | B | — | — |
| 6WCQ | Structure of a substrate-bound DQC ubiquitin ligase | electron microscopy | B | — | 7 (best 0.73) |
| 6WCQ | Structure of a substrate-bound dqc ubiquitin ligase | electron microscopy | B | — | — |
| 8UAH | Structure of BACH1 BTB domain-bound FBXL17 ubiquitin ligase | electron microscopy | B | — | 4 (best 0.67) |
| 8UBU | Cryo-EM structure of dimeric SCF-FBXL17-BACH1BTB E3 ligase complex close conformation | electron microscopy | D, K | — | 15 (best 0.85) |
| Q9UF56 | AlphaFold monomer V2.0 prediction for F-BOX/LRR-repeat protein 17 (Q9UF56) | predicted | A | — | — |
Experiment against prediction
- 6W66 chain B against the predicted model Q9UF56: TM-score 0.99, RMSD 0.82 Å
- 8UAH chain B against the predicted model Q9UF56: TM-score 0.98, RMSD 1.09 Å
- 6WCQ chain B against the predicted model Q9UF56: TM-score 0.97, RMSD 1.24 Å
- 6WCQ chain B against the predicted model Q9UF56: TM-score 0.97, RMSD 1.24 Å
- 8UBU chain K against the predicted model Q9UF56: TM-score 0.88, RMSD 2.68 Å
- 8UBU chain D against the predicted model Q9UF56: TM-score 0.88, RMSD 2.68 Å
Elsewhere
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