UniProt Q9UEE5
Serine/threonine-protein kinase 17A (Q9UEE5)
Serine/threonine-protein kinase 17A (UniProt Q9UEE5), EC 2.7.11.1: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UEE5
- Protein
- Serine/threonine-protein kinase 17A
- EC
- 2.7.11.1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 3 records with a druggable one
Structures
5 records of Q9UEE5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7QUE | The STK17A (DRAK1) Kinase Domain Bound to CKJB68 | x-ray diffraction | A, B | F7I | 4 (best 0.71) |
| 7QUE | The STK17A (DRAK1) kinase domain bound to CKJB68 | x-ray diffraction | A, B | F7I | — |
| 7QUF | The STK17A (DRAK1) Kinase Domain Bound to CK156 | x-ray diffraction | A, B | F8I | 5 (best 0.70) |
| 7QUF | The STK17A (DRAK1) kinase domain bound to CK156 | x-ray diffraction | A, B | F8I | — |
| Q9UEE5 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 17A (Q9UEE5) | predicted | A | — | 3 (best 0.73) |
Ligands
- F7I · ~{N}-(phenylmethyl)-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide · in 2 records
- F8I · ~{N}-~{tert}-butyl-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide · in 2 records
Experiment against prediction
- 7QUE chain A against the predicted model Q9UEE5: TM-score 0.91, RMSD 1.44 Å
- 7QUE chain A against the predicted model Q9UEE5: TM-score 0.91, RMSD 1.44 Å
- 7QUF chain A against the predicted model Q9UEE5: TM-score 0.90, RMSD 1.44 Å
- 7QUF chain A against the predicted model Q9UEE5: TM-score 0.90, RMSD 1.44 Å
- 7QUE chain B against the predicted model Q9UEE5: TM-score 0.89, RMSD 1.95 Å
- 7QUE chain B against the predicted model Q9UEE5: TM-score 0.89, RMSD 1.95 Å
- 7QUF chain B against the predicted model Q9UEE5: TM-score 0.89, RMSD 1.79 Å
- 7QUF chain B against the predicted model Q9UEE5: TM-score 0.89, RMSD 1.79 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.