UniProt Q9UBP6
tRNA (guanine-N(7)-)-methyltransferase (Q9UBP6)
tRNA (guanine-N(7)-)-methyltransferase (UniProt Q9UBP6), EC 2.1.1.-, 2.1.1.33: 12 experimental structures on GenesisL1, 5 ligands bound, 31 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9UBP6
- Protein
- tRNA (guanine-N(7)-)-methyltransferase
- EC
- 2.1.1.-, 2.1.1.33
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 31 · 6 records with a druggable one
Structures
12 records of Q9UBP6 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3CKK | Crystal structure of human methyltransferase-like protein 1 | x-ray diffraction | A | — | — |
| 3CKK | Crystal structure of human methyltransferase-like protein 1 | x-ray diffraction | A | — | — |
| 7OGJ | Crystal structure of human METTL1 in complex with sah | x-ray diffraction | A, B | SO4, CL, PO4 | — |
| 7PL1 | Crystal structure of human METTL1 bound to sinefungin | x-ray diffraction | A | SO4 | — |
| 7U20 | Crystal structure of human METTL1 and WDR4 complex | x-ray diffraction | A | SO4 | 5 (best 0.61) |
| 8CTH | Cryo-EM structure of human METTL1-WDR4-tRNA(Phe) complex | electron microscopy | A | SAH | 4 (best 0.81) |
| 8D58 | Crystal structure of human METTL1-WDR4 complex | x-ray diffraction | A | CL | 2 (best 0.62) |
| 8D59 | Crystal structure of human METTL1 in complex with SAM | x-ray diffraction | A | SAM, SO4, CL | 1 (best 0.53) |
| 8D9K | CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA | electron microscopy | A | — | 6 (best 0.80) |
| 8EG0 | CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA and SAH | electron microscopy | A | SAH | 10 (best 0.84) |
| 8H0N | Crystal structure of the human METTL1-WDR4 complex | x-ray diffraction | B | — | 3 (best 0.49) |
| Q9UBP6 | AlphaFold monomer V2.0 prediction for tRNA (guanine-N(7)-)-methyltransferase (Q9UBP6) | — | — | — |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.