UniProt Q9SJQ6
Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1 (Q9SJQ6)
Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1 (UniProt Q9SJQ6), EC 4.2.99.18: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 31 pockets. Binding sites, druggability and experiment…
- UniProt
- Q9SJQ6
- Protein
- Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
- EC
- 4.2.99.18
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 31 · 4 records with a druggable one
Structures
4 records of Q9SJQ6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YHO | CryoEM structure of Arabidopsis ROS1 in complex with TG mismatch dsDNA at 3.3 Angstroms resolution | electron microscopy | A | SF4 | 7 (best 0.76) |
| 7YHP | CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution | electron microscopy | A | SF4 | 5 (best 0.77) |
| 7YHQ | CryoEM structure of Arabidopsis ROS1 in complex with a covalent-linked reaction intermediate at 3.9… | electron microscopy | A | SF4 | 8 (best 0.78) |
| Q9SJQ6 | AlphaFold monomer V2.0 prediction for DNA GLYCOSYLASE/AP lyase ROS1 (Q9SJQ6) | predicted | A | — | 11 (best 0.73) |
Ligands
- SF4 · Iron/sulfur cluster · in 3 records
Experiment against prediction
- 7YHP chain A against the predicted model Q9SJQ6: TM-score 0.98, RMSD 0.98 Å
- 7YHO chain A against the predicted model Q9SJQ6: TM-score 0.97, RMSD 1.38 Å
- 7YHQ chain A against the predicted model Q9SJQ6: TM-score 0.96, RMSD 1.36 Å
- 7YHQ chain A against the predicted model Q05066: TM-score 0.16, RMSD 5.73 Å
- 7YHO chain A against the predicted model Q05066: TM-score 0.16, RMSD 5.24 Å
- 7YHP chain A against the predicted model Q05066: TM-score 0.15, RMSD 5.02 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.