UniProt Q9QZQ1
Afadin (Q9QZQ1)
Afadin (UniProt Q9QZQ1): 9 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9QZQ1
- Protein
- Afadin
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
10 records of Q9QZQ1 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WLN | Solution structure of the FHA domain of mouse Afadin 6 | solution nmr | A | — | — |
| 1WLN | Solution structure of the fha domain of mouse afadin 6 | solution nmr | A | — | — |
| 1WXA | Solution Structure of Ras-binding Domain in Mouse AF-6 Protein | solution nmr | A | — | — |
| 1WXA | Solution structure of RAS-binding domain in mouse af-6 protein | solution nmr | A | — | — |
| 3AXA | Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3 | x-ray diffraction | A, B | — | 2 (best 0.41) |
| 3AXA | Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3 | x-ray diffraction | A, B | — | 2 (best 0.41) |
| 6AMB | Crystal Structure of the Afadin RA1 domain in complex with HRAS | x-ray diffraction | B | — | 3 (best 0.65) |
| 6AMB | Crystal structure of the afadin RA1 domain in complex with HRAS | x-ray diffraction | B | — | — |
| 9DVA | F-actin binding interface of alpha-E-catenin ABD (cadherin-catenin complex) and afadin | electron microscopy | G | — | 1 (best 0.64) |
| Q9QZQ1 | AlphaFold monomer V2.0 prediction for afadin (Q9QZQ1) | predicted | A | — | — |
Experiment against prediction
- 6AMB chain B against the predicted model Q9QZQ1: TM-score 0.91, RMSD 1.19 Å
- 6AMB chain B against the predicted model Q9QZQ1: TM-score 0.91, RMSD 1.19 Å
- 3AXA chain B against the predicted model Q9QZQ1: TM-score 0.86, RMSD 2.18 Å
- 3AXA chain B against the predicted model Q9QZQ1: TM-score 0.86, RMSD 2.18 Å
- 3AXA chain A against the predicted model Q9QZQ1: TM-score 0.86, RMSD 1.96 Å
- 3AXA chain A against the predicted model Q9QZQ1: TM-score 0.86, RMSD 1.96 Å
- 1WLN chain A against the predicted model Q9QZQ1: TM-score 0.83, RMSD 2.28 Å
- 1WLN chain A against the predicted model Q9QZQ1: TM-score 0.83, RMSD 2.28 Å
- 1WXA chain A against the predicted model Q9QZQ1: TM-score 0.81, RMSD 1.96 Å
- 1WXA chain A against the predicted model Q9QZQ1: TM-score 0.81, RMSD 1.96 Å
Elsewhere
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