UniProt Q9P7N5
Cell division cycle protein 123 (Q9P7N5)
Cell division cycle protein 123 (UniProt Q9P7N5): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9P7N5
- Protein
- Cell division cycle protein 123
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 3 records with a druggable one
Structures
9 records of Q9P7N5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ZGN | Structure Cdc123 complexed with the C-terminal domain of eIF2gamma | x-ray diffraction | A | ATP, MG | 3 (best 0.71) |
| 4ZGN | Structure CDC123 complexed with the C-terminal domain of EIF2GAMMA | x-ray diffraction | A | — | — |
| 4ZGO | Structure of C-terminally truncated Cdc123 from Schizosaccharomyces pombe | x-ray diffraction | A, B | — | 4 (best 0.79) |
| 4ZGO | Structure of C-terminally truncated CDC123 from schizosaccharomyces pombe | x-ray diffraction | A, B | — | — |
| 4ZGP | Structure of Cdc123 from Schizosaccharomyces pombe | x-ray diffraction | A, B | ADP | — |
| 4ZGP | Structure of CDC123 from schizosaccharomyces pombe | x-ray diffraction | A, B | — | — |
| 4ZGQ | Structure of Cdc123 bound to eIF2-gammaDIII domain | x-ray diffraction | A | — | 4 (best 0.73) |
| 4ZGQ | Structure of CDC123 bound to EIF2-gammadiii domain | x-ray diffraction | A | — | — |
| Q9P7N5 | AlphaFold monomer V2.0 prediction for cell division cycle protein 123 (Q9P7N5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4ZGP chain B against the predicted model Q9P7N5: TM-score 0.99, RMSD 0.77 Å
- 4ZGP chain B against the predicted model Q9P7N5: TM-score 0.99, RMSD 0.77 Å
- 4ZGO chain A against the predicted model Q9P7N5: TM-score 0.99, RMSD 0.84 Å
- 4ZGO chain A against the predicted model Q9P7N5: TM-score 0.99, RMSD 0.84 Å
- 4ZGP chain A against the predicted model Q9P7N5: TM-score 0.99, RMSD 0.87 Å
- 4ZGP chain A against the predicted model Q9P7N5: TM-score 0.99, RMSD 0.87 Å
- 4ZGO chain B against the predicted model Q9P7N5: TM-score 0.98, RMSD 0.97 Å
- 4ZGO chain B against the predicted model Q9P7N5: TM-score 0.98, RMSD 0.97 Å
- 4ZGQ chain A against the predicted model Q9P7N5: TM-score 0.92, RMSD 0.69 Å
- 4ZGQ chain A against the predicted model Q9P7N5: TM-score 0.92, RMSD 0.69 Å
Elsewhere
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