UniProt Q9P2H5
Deubiquitinase USP35 peptide (Q9P2H5)
Deubiquitinase USP35 peptide (UniProt Q9P2H5), EC 3.4.19.12: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9P2H5
- Protein
- Deubiquitinase USP35 peptide
- EC
- 3.4.19.12
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 3 records with a druggable one
Structures
4 records of Q9P2H5 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TXK | Crystal structure of USP35 C450S in complex with ubiquitin | x-ray diffraction | A | SO4, ZN | 2 (best 0.50) |
| 5TXK | Crystal structure of USP35 C450S in complex with ubiquitin | x-ray diffraction | A | SO4, ZN | — |
| 7Q44 | Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of… | x-ray diffraction | D, B, F | — | 4 (best 0.72) |
| Q9P2H5 | AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 35 (Q9P2H5) | predicted | A | — | 9 (best 0.74) |
Ligands
Experiment against prediction
- 5TXK chain A against the predicted model Q9P2H5: TM-score 0.99, RMSD 0.63 Å
- 5TXK chain A against the predicted model Q9P2H5: TM-score 0.99, RMSD 0.63 Å
- 7Q44 chain F against the predicted model Q9P2H5: TM-score 0.58, RMSD 0.57 Å
- 7Q44 chain B against the predicted model Q9P2H5: TM-score 0.51, RMSD 0.78 Å
- 7Q44 chain D against the predicted model Q9P2H5: TM-score 0.40, RMSD 1.25 Å
Elsewhere
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