UniProt Q9P1W9
SERINE/THREONINE-protein kinase pim-2 (Q9P1W9)
SERINE/THREONINE-protein kinase pim-2 (UniProt Q9P1W9): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9P1W9
- Protein
- SERINE/THREONINE-protein kinase pim-2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
5 records of Q9P1W9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IWI | Crystal structure of the human PIM2 in complex with a ruthenium organometallic ligand RU1 | x-ray diffraction | A, B | — | — |
| 2IWI | Crystal structure of the human PIM2 in complex with a ruthenium organometallic ligand RU1 | x-ray diffraction | A, B | — | — |
| 4X7Q | PIM2 kinase in complex with Compound 1s | x-ray diffraction | B, A | — | — |
| 4X7Q | PIM2 kinase in complex with compound 1S | x-ray diffraction | B, A | — | — |
| Q9P1W9 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pim-2 (Q9P1W9) | predicted | A | — | 3 (best 0.64) |
Experiment against prediction
- 2IWI chain B against the predicted model Q9P1W9: TM-score 0.99, RMSD 0.67 Å
- 2IWI chain B against the predicted model Q9P1W9: TM-score 0.99, RMSD 0.67 Å
- 2IWI chain A against the predicted model Q9P1W9: TM-score 0.99, RMSD 0.72 Å
- 2IWI chain A against the predicted model Q9P1W9: TM-score 0.99, RMSD 0.72 Å
- 4X7Q chain A against the predicted model Q9P1W9: TM-score 0.98, RMSD 0.76 Å
- 4X7Q chain A against the predicted model Q9P1W9: TM-score 0.98, RMSD 0.76 Å
- 4X7Q chain B against the predicted model Q9P1W9: TM-score 0.98, RMSD 0.83 Å
- 4X7Q chain B against the predicted model Q9P1W9: TM-score 0.98, RMSD 0.83 Å
Elsewhere
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