UniProt Q9P0U3
Sentrin-specific protease 1 (Q9P0U3)
Sentrin-specific protease 1 (UniProt Q9P0U3), EC 3.4.22.-: 20 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9P0U3
- Protein
- Sentrin-specific protease 1
- EC
- 3.4.22.-
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
21 records of Q9P0U3 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CKG | The structure of SENP1 SUMO-2 co-complex suggests a structural basis for discrimination between… | x-ray diffraction | A, B | — | — |
| 2CKG | The structure of SENP1 sumo-2 co-complex suggests a structural basis for discrimination between… | x-ray diffraction | A, B | — | — |
| 2CKH | SENP1-SUMO2 complex | x-ray diffraction | A | — | — |
| 2CKH | SENP1-SUMO2 complex | x-ray diffraction | A | — | — |
| 2G4D | Crystal structure of human SENP1 mutant (C603S) in complex with SUMO-1 | x-ray diffraction | A, C | — | — |
| 2G4D | Crystal structure of human SENP1 mutant (C603S) in complex with sumo-1 | x-ray diffraction | A, C | — | — |
| 2IY0 | SENP1 (mutant) SUMO1 RanGAP | x-ray diffraction | A | — | — |
| 2IY0 | SENP1 (mutant) SUMO1 rangap | x-ray diffraction | A | — | — |
| 2IY1 | SENP1 (mutant) full length SUMO1 | x-ray diffraction | A, C | — | — |
| 2IY1 | SENP1 (mutant) full length SUMO1 | x-ray diffraction | A, C | — | — |
| 2IYC | SENP1 native structure | x-ray diffraction | A, B | — | — |
| 2IYC | SENP1 native structure | x-ray diffraction | A, B | — | — |
| 2IYD | SENP1 covalent complex with SUMO-2 | x-ray diffraction | A | — | — |
| 2IYD | SENP1 covalent complex with sumo-2 | x-ray diffraction | A | — | — |
| 2XPH | Crystal structure of human SENP1 with the bound cobalt | x-ray diffraction | A, B | — | — |
| 2XPH | Crystal structure of human SENP1 with the bound cobalt | x-ray diffraction | A, B | — | — |
| 2XRE | Detection of cobalt in previously unassigned human SENP1 structure | x-ray diffraction | A, B | — | — |
| 2XRE | Detection of cobalt in previously unassigned human SENP1 structure | x-ray diffraction | A, B | — | — |
| 6NNQ | Non-covalent structure of SENP1 in complex with SUMO2 | x-ray diffraction | A | — | 4 (best 0.64) |
| 6NNQ | Non-covalent structure of SENP1 in complex with SUMO2 | x-ray diffraction | A | — | — |
| Q9P0U3 | AlphaFold monomer V2.0 prediction for sentrin-specific protease 1 (Q9P0U3) | predicted | A | — | 6 (best 0.53) |
Experiment against prediction
- 2IYC chain A against the predicted model Q9P0U3: TM-score 1.00, RMSD 0.36 Å
- 2IYC chain A against the predicted model Q9P0U3: TM-score 1.00, RMSD 0.36 Å
- 2CKG chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.40 Å
- 2CKG chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.40 Å
- 2IY1 chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.44 Å
- 2IY1 chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.44 Å
- 2G4D chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.40 Å
- 2G4D chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.40 Å
- 2IY0 chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.46 Å
- 2IY0 chain A against the predicted model Q9P0U3: TM-score 0.99, RMSD 0.46 Å
Elsewhere
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