UniProt Q9NZN8
CCR4-not transcription complex subunit 2 (Q9NZN8)
CCR4-not transcription complex subunit 2 (UniProt Q9NZN8): 8 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NZN8
- Protein
- CCR4-not transcription complex subunit 2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 14 · 1 record with a druggable one
Structures
9 records of Q9NZN8 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C0D | Structure of the NOT module of the human CCR4-NOT complex (CNOT1-CNOT2-CNOT3) | x-ray diffraction | B | — | — |
| 4C0D | Structure of the not module of the human CCR4-not complex (CNOT1-CNOT2-CNOT3) | x-ray diffraction | B | — | — |
| 4C0F | Structure of the NOT-box domain of human CNOT2 | x-ray diffraction | A, B, C, D | — | — |
| 4C0F | Structure of the not-box domain of human CNOT2 | x-ray diffraction | A, B, C, D | — | — |
| 5FU6 | NOT module of the human CCR4-NOT complex (Crystallization mutant) | x-ray diffraction | B, E | — | 14 (best 0.78) |
| 5FU6 | Not module of the human CCR4-not complex (crystallization mutant) | x-ray diffraction | B, E | — | — |
| 5FU7 | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | x-ray diffraction | B, F | — | — |
| 5FU7 | Drosophila nanos nbr peptide bound to the not module of the human CCR4-not complex | x-ray diffraction | B, F | — | — |
| Q9NZN8 | AlphaFold monomer V2.0 prediction for CCR4-not transcription complex subunit 2 (Q9NZN8) | predicted | A | — | — |
Experiment against prediction
- 5FU7 chain B against the predicted model Q9NZN8: TM-score 0.96, RMSD 1.24 Å
- 5FU7 chain B against the predicted model Q9NZN8: TM-score 0.96, RMSD 1.24 Å
- 5FU7 chain F against the predicted model Q9NZN8: TM-score 0.96, RMSD 1.28 Å
- 5FU7 chain F against the predicted model Q9NZN8: TM-score 0.96, RMSD 1.28 Å
- 5FU6 chain B against the predicted model Q9NZN8: TM-score 0.95, RMSD 1.32 Å
- 5FU6 chain B against the predicted model Q9NZN8: TM-score 0.95, RMSD 1.32 Å
- 5FU6 chain E against the predicted model Q9NZN8: TM-score 0.94, RMSD 1.50 Å
- 5FU6 chain E against the predicted model Q9NZN8: TM-score 0.94, RMSD 1.50 Å
- 4C0D chain B against the predicted model Q9NZN8: TM-score 0.93, RMSD 1.48 Å
- 4C0D chain B against the predicted model Q9NZN8: TM-score 0.93, RMSD 1.48 Å
Elsewhere
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