UniProt Q9NZ71

Regulator of telomere elongation helicase 1 (Q9NZ71)

Regulator of telomere elongation helicase 1 (UniProt Q9NZ71), EC 3.6.4.12: 3 experimental structures and 1 predicted model on GenesisL1, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9NZ71
Protein: Regulator of telomere elongation helicase 1
EC: 3.6.4.12
Experimental structures: 3
Predicted models: 1
Pockets: 34 · 4 records with a druggable one

Structures

4 records of Q9NZ71 in the MolNFT archive: 3 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7WU8	Crystal structure of Harmonin-homology domain 2 (HHD2) of human RTEL1	x-ray diffraction	A, B, C, D, E, F, G	—	5 (best 0.56)
8P8H	Crystal structure of HHD2 domain of hRTEL1	x-ray diffraction	A, B, C, D, E, F, G	—	7 (best 0.62)
8YA8	The crystal structure of human Rtel1 HHD2 domain	x-ray diffraction	A, B, C, D, E, F, G	—	7 (best 0.59)
Q9NZ71	AlphaFold monomer V2.0 prediction for regulator of telomere elongation helicase 1 (Q9NZ71)	predicted	A	—	15 (best 0.83)

Experiment against prediction

8P8H chain F against the predicted model Q9NZ71: TM-score 0.99, RMSD 0.33 Å
8YA8 chain A against the predicted model Q9NZ71: TM-score 0.99, RMSD 0.36 Å
8P8H chain C against the predicted model Q9NZ71: TM-score 0.99, RMSD 0.36 Å
8P8H chain A against the predicted model Q9NZ71: TM-score 0.98, RMSD 0.41 Å
8P8H chain E against the predicted model Q9NZ71: TM-score 0.98, RMSD 0.42 Å
8YA8 chain D against the predicted model Q9NZ71: TM-score 0.98, RMSD 0.59 Å
7WU8 chain E against the predicted model Q9NZ71: TM-score 0.98, RMSD 0.50 Å
7WU8 chain C against the predicted model Q9NZ71: TM-score 0.98, RMSD 0.52 Å
8YA8 chain F against the predicted model Q9NZ71: TM-score 0.98, RMSD 0.50 Å
8YA8 chain B against the predicted model Q9NZ71: TM-score 0.97, RMSD 0.54 Å

Elsewhere

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