UniProt Q9NYA1
Sphingosine kinase 1 (Q9NYA1)
Sphingosine kinase 1 (UniProt Q9NYA1): 10 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NYA1
- Protein
- Sphingosine kinase 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
11 records of Q9NYA1 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3VZB | Crystal structure of Sphingosine Kinase 1 | x-ray diffraction | A, B, C | — | — |
| 3VZB | Crystal structure of sphingosine kinase 1 | x-ray diffraction | A, B, C | — | — |
| 3VZC | Crystal structure of Sphingosine Kinase 1 with inhibitor | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3VZC | Crystal structure of sphingosine kinase 1 with inhibitor | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3VZD | Crystal structure of Sphingosine Kinase 1 with inhibitor and ADP | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3VZD | Crystal structure of sphingosine kinase 1 with inhibitor and ADP | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L02 | Crystal Structure of SphK1 with inhibitor | x-ray diffraction | A, B, C | — | — |
| 4L02 | Crystal structure of SPHK1 with inhibitor | x-ray diffraction | A, B, C | — | — |
| 4V24 | Sphingosine kinase 1 in complex with PF-543 | x-ray diffraction | A, B | — | — |
| 4V24 | Sphingosine kinase 1 in complex with pf-543 | x-ray diffraction | A, B | — | — |
| Q9NYA1 | AlphaFold monomer V2.0 prediction for sphingosine kinase 1 (Q9NYA1) | predicted | A | — | 5 (best 0.81) |
Experiment against prediction
- 3VZC chain B against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.49 Å
- 3VZC chain B against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.49 Å
- 3VZD chain B against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.54 Å
- 3VZD chain B against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.54 Å
- 3VZD chain E against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.56 Å
- 3VZD chain E against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.56 Å
- 3VZC chain E against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.62 Å
- 3VZC chain E against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.62 Å
- 3VZD chain A against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.70 Å
- 3VZD chain A against the predicted model Q9NYA1: TM-score 0.99, RMSD 0.70 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.