UniProt Q9NY12
H/ACA ribonucleoprotein complex subunit 1 (Q9NY12)
H/ACA ribonucleoprotein complex subunit 1 (UniProt Q9NY12): 8 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NY12
- Protein
- H/ACA ribonucleoprotein complex subunit 1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 16 · 5 records with a druggable one
Structures
9 records of Q9NY12 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BGB | The H/ACA RNP lobe of human telomerase | electron microscopy | H, D | — | 3 (best 0.79) |
| 7BGB | The H/ACA rnp lobe of human telomerase | electron microscopy | H, D | — | — |
| 7TRC | Human telomerase H/ACA RNP at 3.3 Angstrom | electron microscopy | H, D | — | 3 (best 0.76) |
| 7TRC | Human telomerase H/ACA rnp at 3.3 ångström | electron microscopy | H, D | — | — |
| 7V9A | biogenesis module of human telomerase holoenzyme | electron microscopy | D, H | — | 4 (best 0.74) |
| 7V9A | Biogenesis module of human telomerase holoenzyme | electron microscopy | D, H | — | — |
| 8OUE | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation | electron microscopy | D, H | — | 2 (best 0.75) |
| 8OUF | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open conformation | electron microscopy | D, H | — | 4 (best 0.84) |
| Q9NY12 | AlphaFold monomer V2.0 prediction for H/ACA ribonucleoprotein complex subunit 1 (Q9NY12) | predicted | A | — | — |
Experiment against prediction
- 8OUE chain H against the predicted model Q9NY12: TM-score 0.95, RMSD 0.92 Å
- 8OUF chain H against the predicted model Q9NY12: TM-score 0.94, RMSD 0.96 Å
- 8OUE chain D against the predicted model Q9NY12: TM-score 0.94, RMSD 0.96 Å
- 7TRC chain H against the predicted model Q9NY12: TM-score 0.94, RMSD 0.98 Å
- 7TRC chain H against the predicted model Q9NY12: TM-score 0.94, RMSD 0.98 Å
- 8OUF chain D against the predicted model Q9NY12: TM-score 0.93, RMSD 1.03 Å
- 7BGB chain H against the predicted model Q9NY12: TM-score 0.93, RMSD 1.04 Å
- 7BGB chain H against the predicted model Q9NY12: TM-score 0.93, RMSD 1.04 Å
- 7TRC chain D against the predicted model Q9NY12: TM-score 0.91, RMSD 1.21 Å
- 7TRC chain D against the predicted model Q9NY12: TM-score 0.91, RMSD 1.21 Å
Elsewhere
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