UniProt Q9NXV2
BTB/POZ domain-containing protein KCTD5 (Q9NXV2)
BTB/POZ domain-containing protein KCTD5 (UniProt Q9NXV2): 11 experimental structures and 1 predicted model on GenesisL1, 92 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NXV2
- Protein
- BTB/POZ domain-containing protein KCTD5
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 92 · 5 records with a druggable one
Structures
12 records of Q9NXV2 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DRX | X-ray crystal structure of human KCTD5 protein crystallized in high-salt buffer | x-ray diffraction | A, B, C, D, E | — | — |
| 3DRX | X-ray crystal structure of human KCTD5 protein crystallized in high- salt buffer | x-ray diffraction | A, B, C, D, E | — | — |
| 3DRY | X-ray crystal structure of human KCTD5 protein crystallized in low-salt buffer | x-ray diffraction | A, B, C, D, E | — | — |
| 3DRY | X-ray crystal structure of human KCTD5 protein crystallized in low- salt buffer | x-ray diffraction | A, B, C, D, E | — | — |
| 3DRZ | X-ray crystal structure of the N-terminal BTB domain of human KCTD5 protein | x-ray diffraction | A, B, C, D, E | — | — |
| 3DRZ | X-ray crystal structure of the N-terminal btb domain of human KCTD5 protein | x-ray diffraction | A, B, C, D, E | — | — |
| 8U7Z | KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(CTD)/Gbeta1gamma2 | electron microscopy | K1, K2, K3, K4, K5 | — | 19 (best 0.82) |
| 8U80 | KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(BTB)/Cullin3(NTD) | electron microscopy | K1, K2, K3, K4, K5 | — | 16 (best 0.72) |
| 8U82 | KCTD5/Cullin3/Gbeta1gamma2 Complex: State B From Composite RELION Multi-body Refinement Map | electron microscopy | K1, K2, K3, K4, K5 | — | 20 (best 0.84) |
| 8U83 | KCTD5/Cullin3/Gbeta1gamma2 Complex: State C From Composite RELION Multi-body Refinement Map | electron microscopy | K1, K2, K3, K4, K5 | — | 19 (best 0.84) |
| 8U84 | KCTD5/Cullin3/Gbeta1gamma2 Complex: State D From Composite RELION Multi-body Refinement Map | electron microscopy | K1, K2, K3, K4, K5 | — | 17 (best 0.83) |
| Q9NXV2 | AlphaFold monomer V2.0 prediction for BTB/POZ domain-containing protein KCTD5 (Q9NXV2) | predicted | A | — | 1 (best 0.26) |
Experiment against prediction
- 3DRZ chain D against the predicted model Q9NXV2: TM-score 0.99, RMSD 0.43 Å
- 3DRZ chain D against the predicted model Q9NXV2: TM-score 0.99, RMSD 0.43 Å
- 3DRZ chain C against the predicted model Q9NXV2: TM-score 0.98, RMSD 0.49 Å
- 3DRZ chain C against the predicted model Q9NXV2: TM-score 0.98, RMSD 0.49 Å
- 3DRZ chain E against the predicted model Q9NXV2: TM-score 0.97, RMSD 0.94 Å
- 3DRZ chain E against the predicted model Q9NXV2: TM-score 0.97, RMSD 0.94 Å
- 3DRZ chain A against the predicted model Q9NXV2: TM-score 0.97, RMSD 0.94 Å
- 3DRZ chain A against the predicted model Q9NXV2: TM-score 0.97, RMSD 0.94 Å
- 8U80 chain K1 against the predicted model Q9NXV2: TM-score 0.93, RMSD 1.06 Å
- 3DRX chain E against the predicted model Q9NXV2: TM-score 0.88, RMSD 1.97 Å
Elsewhere
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