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UniProt Q9NXS2

Glutaminyl-peptide cyclotransferase-like protein (Q9NXS2)

Glutaminyl-peptide cyclotransferase-like protein (UniProt Q9NXS2), EC 2.3.2.5: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 41 pockets. Binding sites, druggability and experiment against…

UniProt
Q9NXS2
Protein
Glutaminyl-peptide cyclotransferase-like protein
EC
2.3.2.5
Experimental structures
12
Predicted models
1
Ligands
3
Pockets
41 · 2 records with a druggable one

Structures

13 records of Q9NXS2 in the MolNFT archive: 12 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
3PB4Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase at pH 6.0x-ray diffractionX——
3PB4Crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase at pH 6.0x-ray diffractionX——
3PB6Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase at pH 6.5x-ray diffractionX——
3PB6Crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase at pH 6.5x-ray diffractionX——
3PB7Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex…x-ray diffractionX——
3PB7Crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase in complex…x-ray diffractionX——
3PB8Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex…x-ray diffractionX——
3PB8Crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase in complex…x-ray diffractionX——
3PB9Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex…x-ray diffractionX——
3PB9Crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase in complex…x-ray diffractionX——
8XFVCrystal structure of human Golgi resident glutaminyl cyclase in complex with…x-ray diffractionX, A, B, C, D, E, F, G, H, I, JZN, A1D4620 (best 0.82)
8XGACrystal structure of human Golgi resident glutaminyl cyclase in complex with…x-ray diffractionA, B, C, D, E, F, G, H, I, J, KZN, A1D4720 (best 0.81)
Q9NXS2AlphaFold monomer V2.0 prediction for glutaminyl-peptide cyclotransferase-like protein (Q9NXS2)predictedA—1 (best 0.40)

Ligands

  • ZN · Zinc ion · in 2 records
  • A1D46 · 3-(1~{H}-benzimidazol-5-ylmethylidene)-4-piperidin-4-yloxy-1~{H}-indol-2-one · in 1 record
  • A1D47 · (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-(oxan-4-yloxy)-1~{H}-indol-2-one · in 1 record

Experiment against prediction

Elsewhere

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