UniProt Q9NXR7
BRISC and BRCA1-A complex member 2,BRCC45 (BRE, BRISC and BRCA1-A complex member 2) (Q9NXR7)
BRISC and BRCA1-A complex member 2,BRCC45 (BRE, BRISC and BRCA1-A complex member 2) (UniProt Q9NXR7): 4 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9NXR7
- Protein
- BRISC and BRCA1-A complex member 2,BRCC45 (BRE, BRISC and BRCA1-A complex…
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
5 records of Q9NXR7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6H3C | Cryo-EM structure of the BRISC complex bound to SHMT2 | electron microscopy | C, H | — | — |
| 6H3C | Cryo-EM structure of the brisc complex bound to SHMT2 | electron microscopy | C, H | — | — |
| 6R8F | Cryo-EM structure of the Human BRISC-SHMT2 complex | electron microscopy | E, G | — | 9 (best 0.76) |
| 6R8F | Cryo-EM structure of the human brisc-SHMT2 complex | electron microscopy | E, G | — | — |
| Q9NXR7 | AlphaFold monomer V2.0 prediction for brisc and BRCA1-a complex member 2 (Q9NXR7) | predicted | A | — | — |
Experiment against prediction
- 6R8F chain E against the predicted model Q9NXR7: TM-score 0.88, RMSD 2.37 Å
- 6R8F chain E against the predicted model Q9NXR7: TM-score 0.88, RMSD 2.37 Å
- 6R8F chain G against the predicted model Q9NXR7: TM-score 0.88, RMSD 2.37 Å
- 6R8F chain G against the predicted model Q9NXR7: TM-score 0.88, RMSD 2.37 Å
- 6H3C chain C against the predicted model Q9NXR7: TM-score 0.85, RMSD 3.14 Å
- 6H3C chain C against the predicted model Q9NXR7: TM-score 0.85, RMSD 3.14 Å
- 6H3C chain H against the predicted model Q9NXR7: TM-score 0.85, RMSD 3.14 Å
- 6H3C chain H against the predicted model Q9NXR7: TM-score 0.85, RMSD 3.14 Å
Elsewhere
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