UniProt Q9NVX7
Kelch repeat and BTB domain-containing protein 4 (Q9NVX7)
Kelch repeat and BTB domain-containing protein 4 (UniProt Q9NVX7): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NVX7
- Protein
- Kelch repeat and BTB domain-containing protein 4
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 54 · 6 records with a druggable one
Structures
8 records of Q9NVX7 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EQX | Solution structure of the BACK domain of Kelch repeat and BTB domain-containing protein 4 | solution nmr | A | — | — |
| 2EQX | Solution structure of the back domain of kelch repeat and btb domain- containing protein 4 | solution nmr | A | — | — |
| 8VOJ | The Cryo-EM structure of LSD1-CoREST-HDAC1 in complex with KBTBD4 enhanced by UM171 and IP6 | electron microscopy | A, B | IHP, A1ACV | 9 (best 0.79) |
| 8VPQ | The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML | electron microscopy | A, B | IHP | 12 (best 0.79) |
| 8VRT | The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4R313PRR mutant | electron microscopy | A, B | IHP | 8 (best 0.78) |
| 9DTG | The cryo-EM structure of apo KBTBD4 | electron microscopy | A, B | — | 10 (best 0.79) |
| 9DTQ | The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant | electron microscopy | B, E | IHP | 12 (best 0.78) |
| Q9NVX7 | AlphaFold monomer V2.0 prediction for kelch repeat and btb domain- containing protein 4 (Q9NVX7) | predicted | A | — | 3 (best 0.75) |
Ligands
Experiment against prediction
- 2EQX chain A against the predicted model Q9NVX7: TM-score 0.89, RMSD 1.39 Å
- 2EQX chain A against the predicted model Q9NVX7: TM-score 0.89, RMSD 1.39 Å
- 8VRT chain B against the predicted model Q9NVX7: TM-score 0.54, RMSD 2.48 Å
- 9DTG chain A against the predicted model Q9NVX7: TM-score 0.54, RMSD 2.49 Å
- 8VOJ chain A against the predicted model Q9NVX7: TM-score 0.54, RMSD 2.45 Å
- 8VRT chain A against the predicted model Q9NVX7: TM-score 0.54, RMSD 2.43 Å
- 8VOJ chain B against the predicted model Q9NVX7: TM-score 0.54, RMSD 2.51 Å
- 8VPQ chain A against the predicted model Q9NVX7: TM-score 0.53, RMSD 2.53 Å
- 9DTQ chain B against the predicted model Q9NVX7: TM-score 0.53, RMSD 2.70 Å
- 8VPQ chain B against the predicted model Q9NVX7: TM-score 0.53, RMSD 2.57 Å
Elsewhere
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