UniProt Q9NVI1
Fanconi anemia group I protein (Q9NVI1)
Fanconi anemia group I protein (UniProt Q9NVI1): 5 experimental structures and 1 predicted model on GenesisL1, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NVI1
- Protein
- Fanconi anemia group I protein
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 53 · 4 records with a druggable one
Structures
6 records of Q9NVI1 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7AY1 | Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and FANCI | electron microscopy | A | — | 12 (best 0.70) |
| 7AY1 | Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and fanci | electron microscopy | A | — | — |
| 7ZF1 | Structure of ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA | electron microscopy | A | — | 16 (best 0.86) |
| 8A9J | Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 without ML323… | electron microscopy | A | — | 13 (best 0.72) |
| 8A9K | Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 with ML323 (consensus… | electron microscopy | A | — | 12 (best 0.74) |
| Q9NVI1 | AlphaFold monomer V2.0 prediction for fanconi anemia group I protein (Q9NVI1) | predicted | A | — | — |
Experiment against prediction
- 8A9K chain A against the predicted model Q9NVI1: TM-score 0.96, RMSD 2.20 Å
- 8A9J chain A against the predicted model Q9NVI1: TM-score 0.96, RMSD 2.17 Å
- 7ZF1 chain A against the predicted model Q9NVI1: TM-score 0.96, RMSD 2.40 Å
- 7AY1 chain A against the predicted model Q9NVI1: TM-score 0.95, RMSD 2.65 Å
- 7AY1 chain A against the predicted model Q9NVI1: TM-score 0.95, RMSD 2.65 Å
Elsewhere
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