UniProt Q9NUX5
Protection of telomeres protein 1 (Q9NUX5)
Protection of telomeres protein 1 (UniProt Q9NUX5): 21 experimental structures on GenesisL1, 2 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9NUX5
- Protein
- Protection of telomeres protein 1
- Experimental structures
- 21
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 27 · 5 records with a druggable one
Structures
21 records of Q9NUX5 in the MolNFT archive: 21 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XJV | Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG) | x-ray diffraction | A | — | — |
| 1XJV | Crystal structure of human POT1 bound to telomeric single- stranded DNA (ttagggttag) | x-ray diffraction | A | — | — |
| 3KJO | Crystal Structure of hPOT1V2-dTrUd(AGGGTTAG) | x-ray diffraction | A | — | — |
| 3KJO | Crystal structure of HPOT1V2-DTRUD(AGGGTTAG) | x-ray diffraction | A | — | — |
| 3KJP | Crystal Structure of hPOT1V2-GGTTAGGGTTAG | x-ray diffraction | A | — | — |
| 3KJP | Crystal structure of HPOT1V2-ggttagggttag | x-ray diffraction | A | — | — |
| 5H65 | Crystal structure of human POT1 and TPP1 | x-ray diffraction | A | ZN | 3 (best 0.67) |
| 5H65 | Crystal structure of human POT1 and TPP1 | x-ray diffraction | A | — | — |
| 5UN7 | Structure of the human POT1-TPP1 telomeric complex | x-ray diffraction | A | ZN, K | — |
| 5UN7 | Structure of the human POT1-TPP1 telomeric complex | x-ray diffraction | A | ZN, K | — |
| 7QXB | Cryo-EM MAP of human telomerase-DNA-TPP1-POT1 complex (sharpened MAP) | electron microscopy | P | — | — |
| 7QXS | Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) | electron microscopy | P | — | — |
| 7S1O | Structure of human POT1C | x-ray diffraction | A, B | ZN | 6 (best 0.66) |
| 7S1O | Structure of human POT1C | x-ray diffraction | A, B | ZN | — |
| 7S1T | Structure of the human POT1-TPP1 complex | x-ray diffraction | A, D, G, J | ZN | — |
| 7S1U | Structure of human POT1C | x-ray diffraction | A, B | ZN | — |
| 7S1U | Structure of human POT1C | x-ray diffraction | A, B | ZN | — |
| 8SH0 | Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric DNA… | x-ray diffraction | A | — | 4 (best 0.60) |
| 8SH1 | Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric… | x-ray diffraction | A | — | 7 (best 0.58) |
| 8SOK | Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA | electron microscopy | D | ZN | 7 (best 0.84) |
| Q9NUX5 | AlphaFold monomer V2.0 prediction for protection of telomeres protein 1 (Q9NUX5) | — | — | — |
Ligands
Elsewhere
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