UniProt Q9NTX7
E3 ubiquitin-protein ligase RNF146 (Q9NTX7)
E3 ubiquitin-protein ligase RNF146 (UniProt Q9NTX7): 4 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NTX7
- Protein
- E3 ubiquitin-protein ligase RNF146
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 5 · 0 records with a druggable one
Structures
5 records of Q9NTX7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2D8T | Solution structure of the RING domain of the human RING finger protein 146 | solution nmr | A | — | — |
| 2D8T | Solution structure of the ring domain of the human ring finger protein 146 | solution nmr | A | — | — |
| 3V3L | Crystal structure of human RNF146 WWE domain in complex with iso-ADPRibose | x-ray diffraction | A, B | — | — |
| 3V3L | Crystal structure of human RNF146 wwe domain in complex with iso- adpribose | x-ray diffraction | A, B | — | — |
| Q9NTX7 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF146 (Q9NTX7) | predicted | A | — | 5 (best 0.48) |
Experiment against prediction
- 3V3L chain A against the predicted model Q9NTX7: TM-score 0.97, RMSD 0.89 Å
- 3V3L chain A against the predicted model Q9NTX7: TM-score 0.97, RMSD 0.89 Å
- 3V3L chain B against the predicted model Q9NTX7: TM-score 0.95, RMSD 1.04 Å
- 3V3L chain B against the predicted model Q9NTX7: TM-score 0.95, RMSD 1.04 Å
- 2D8T chain A against the predicted model Q9NTX7: TM-score 0.65, RMSD 2.56 Å
- 2D8T chain A against the predicted model Q9NTX7: TM-score 0.65, RMSD 2.56 Å
Elsewhere
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