UniProt Q9NRW3
Probable DNA dC->dU-editing enzyme APOBEC-3C (Q9NRW3)
Probable DNA dC->dU-editing enzyme APOBEC-3C (UniProt Q9NRW3), EC 3.5.4.-: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NRW3
- Protein
- Probable DNA dC->dU-editing enzyme APOBEC-3C
- EC
- 3.5.4.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 14 · 4 records with a druggable one
Structures
5 records of Q9NRW3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3VM8 | Crystal structure of the human APOBEC3C having HIV-1 Vif-binding interface | x-ray diffraction | A, B | ZN | 4 (best 0.68) |
| 3VM8 | Crystal structure of the human APOBEC3C having HIV-1 vif-binding interface | x-ray diffraction | A, B | ZN | 4 (best 0.68) |
| 3VOW | Crystal Structure of the Human APOBEC3C having HIV-1 Vif-binding Interface | x-ray diffraction | A, B | ZN, CL | 3 (best 0.63) |
| 3VOW | Crystal structure of the human APOBEC3C having HIV-1 vif-binding interface | x-ray diffraction | A, B | ZN, CL | 3 (best 0.63) |
| Q9NRW3 | AlphaFold monomer V2.0 prediction for DNA dc->du-editing enzyme apobec-3C (Q9NRW3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3VOW chain A against the predicted model Q9NRW3: TM-score 0.96, RMSD 1.68 Å
- 3VOW chain A against the predicted model Q9NRW3: TM-score 0.96, RMSD 1.68 Å
- 3VM8 chain A against the predicted model Q9NRW3: TM-score 0.95, RMSD 1.63 Å
- 3VM8 chain A against the predicted model Q9NRW3: TM-score 0.95, RMSD 1.63 Å
- 3VOW chain B against the predicted model Q9NRW3: TM-score 0.95, RMSD 1.76 Å
- 3VOW chain B against the predicted model Q9NRW3: TM-score 0.95, RMSD 1.76 Å
- 3VM8 chain B against the predicted model Q9NRW3: TM-score 0.95, RMSD 1.74 Å
- 3VM8 chain B against the predicted model Q9NRW3: TM-score 0.95, RMSD 1.74 Å
Elsewhere
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