UniProt Q9NR22
Protein arginine N-methyltransferase 8 (Q9NR22)
Protein arginine N-methyltransferase 8 (UniProt Q9NR22), EC 2.1.1.125: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NR22
- Protein
- Protein arginine N-methyltransferase 8
- EC
- 2.1.1.125
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
5 records of Q9NR22 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4X41 | Crystal Structure of Protein Arginine Methyltransferase PRMT8 | x-ray diffraction | A, B | SAH | 7 (best 0.60) |
| 4X41 | Crystal structure of protein arginine methyltransferase PRMT8 | x-ray diffraction | A, B | — | — |
| 5DST | Crystal structure of human PRMT8 in complex with SAH | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O | — | — |
| 5DST | Crystal structure of human PRMT8 in complex with sah | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O | — | — |
| Q9NR22 | AlphaFold monomer V2.0 prediction for protein arginine N-methyltransferase 8 (Q9NR22) | predicted | A | — | — |
Ligands
- SAH · S-adenosyl-L-homocysteine · in 1 record
Experiment against prediction
- 5DST chain G against the predicted model Q9NR22: TM-score 0.99, RMSD 0.35 Å
- 5DST chain G against the predicted model Q9NR22: TM-score 0.99, RMSD 0.35 Å
- 5DST chain K against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain K against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain O against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain O against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain B against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain B against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain D against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
- 5DST chain D against the predicted model Q9NR22: TM-score 0.99, RMSD 0.36 Å
Elsewhere
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