UniProt Q9NPG1
Frizzled-3 (Q9NPG1)
Frizzled-3 (UniProt Q9NPG1): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NPG1
- Protein
- Frizzled-3
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 23 · 4 records with a druggable one
Structures
5 records of Q9NPG1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JHC | FZD3 in inactive state | electron microscopy | R | — | 7 (best 0.76) |
| 8JHI | FZD3-Gs complex | electron microscopy | R | — | 5 (best 0.81) |
| 8Q7O | Crystal structure of the FZD3 cysteine-rich domain in complex with a nanobody (14478) | x-ray diffraction | C, D | NAG, SO4 | 3 (best 0.72) |
| 8QW4 | FZD3 in complex with nanobody 9 | electron microscopy | A | — | 8 (best 0.79) |
| Q9NPG1 | AlphaFold monomer V2.0 prediction for frizzled-3 (Q9NPG1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8JHI chain R against the predicted model Q9NPG1: TM-score 0.93, RMSD 2.04 Å
- 8QW4 chain A against the predicted model Q9NPG1: TM-score 0.90, RMSD 2.41 Å
- 8Q7O chain D against the predicted model Q9NPG1: TM-score 0.82, RMSD 2.02 Å
- 8Q7O chain C against the predicted model Q9NPG1: TM-score 0.79, RMSD 2.34 Å
- 8JHC chain R against the predicted model Q9NPG1: TM-score 0.76, RMSD 1.23 Å
- 8JHC chain R against the predicted model P0ABE7: TM-score 0.23, RMSD 1.60 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.