UniProt Q9NPF5
DNA methyltransferase 1-associated protein 1 (Q9NPF5)
DNA methyltransferase 1-associated protein 1 (UniProt Q9NPF5): 13 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NPF5
- Protein
- DNA methyltransferase 1-associated protein 1
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 21 · 8 records with a druggable one
Structures
14 records of Q9NPF5 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3HM5 | SANT domain of human DNA methyltransferase 1 associated protein 1 | x-ray diffraction | A | — | — |
| 3HM5 | Sant domain of human DNA methyltransferase 1 associated protein 1 | x-ray diffraction | A | — | — |
| 4IEJ | Crystal structure of a DNA methyltransferase 1 associated protein 1 (DMAP1) from Homo sapiens at… | x-ray diffraction | A | — | — |
| 4IEJ | Crystal structure of a DNA methyltransferase 1 associated protein 1 (DMAP1) from homo sapiens at… | x-ray diffraction | A | — | — |
| 8QR1 | Cryo-EM structure of the human Tip60 complex | electron microscopy | F | — | 1 (best 0.77) |
| 8X15 | Structure of nucleosome-bound SRCAP-C in the apo state | electron microscopy | V | — | 1 (best 0.82) |
| 8X19 | Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state | electron microscopy | V | — | 1 (best 0.84) |
| 8X1C | Structure of nucleosome-bound SRCAP-C in the ADP-bound state | electron microscopy | V | — | 1 (best 0.85) |
| 8XVG | Structure of human NuA4/TIP60 complex | electron microscopy | G | — | — |
| 8XVT | The core subcomplex of human NuA4/TIP60 complex | electron microscopy | G | — | 2 (best 0.74) |
| 9C57 | Reconstituted P400 Subcomplex of the human TIP60 complex | electron microscopy | I | — | 2 (best 0.83) |
| 9C62 | P400 subcomplex of the native human TIP60 complex | electron microscopy | I | — | 2 (best 0.88) |
| 9C6N | ARP module of the human TIP60 complex | electron microscopy | I | — | 11 (best 0.80) |
| Q9NPF5 | AlphaFold monomer V2.0 prediction for DNA methyltransferase 1-associated protein 1 (Q9NPF5) | predicted | A | — | — |
Experiment against prediction
- 3HM5 chain A against the predicted model Q9NPF5: TM-score 0.99, RMSD 0.28 Å
- 3HM5 chain A against the predicted model Q9NPF5: TM-score 0.99, RMSD 0.28 Å
- 4IEJ chain A against the predicted model Q9NPF5: TM-score 0.98, RMSD 0.55 Å
- 4IEJ chain A against the predicted model Q9NPF5: TM-score 0.98, RMSD 0.55 Å
- 8X19 chain V against the predicted model Q9NPF5: TM-score 0.69, RMSD 3.81 Å
- 8X1C chain V against the predicted model Q9NPF5: TM-score 0.67, RMSD 3.76 Å
- 9C6N chain I against the predicted model Q9NPF5: TM-score 0.66, RMSD 3.96 Å
- 8X15 chain V against the predicted model Q9NPF5: TM-score 0.66, RMSD 3.87 Å
- 8XVG chain G against the predicted model Q9NPF5: TM-score 0.64, RMSD 4.41 Å
- 8XVT chain G against the predicted model Q9NPF5: TM-score 0.64, RMSD 4.41 Å
Elsewhere
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