UniProt Q9NPD3
Exosome complex component RRP41 (Q9NPD3)
Exosome complex component RRP41 (UniProt Q9NPD3): 11 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NPD3
- Protein
- Exosome complex component RRP41
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 22 · 5 records with a druggable one
Structures
12 records of Q9NPD3 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NN6 | Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4… | x-ray diffraction | B | — | — |
| 2NN6 | Structure of the human RNA exosome composed of RRP41, RRP45, RRP46, RRP43, MTR3, RRP42, CSL4, RRP4… | x-ray diffraction | B | — | — |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | B | — | 7 (best 0.86) |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | B | — | — |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction | electron microscopy | B | — | 7 (best 0.85) |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite MAP after focused reconstruction | electron microscopy | B | — | — |
| 6H25 | Human nuclear RNA exosome EXO-10-MPP6 complex | electron microscopy | B | — | — |
| 6H25 | Human nuclear RNA exosome exo-10-MPP6 complex | electron microscopy | B | — | — |
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | L | — | 1 (best 0.87) |
| 9G8N | 80S-bound human Ski2-exosome complex | electron microscopy | L | — | 5 (best 0.83) |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | N | — | 2 (best 0.84) |
| Q9NPD3 | AlphaFold monomer V2.0 prediction for exosome complex component RRP41 (Q9NPD3) | predicted | A | — | — |
Experiment against prediction
- 6D6R chain B against the predicted model Q9NPD3: TM-score 0.98, RMSD 0.91 Å
- 6D6R chain B against the predicted model Q9NPD3: TM-score 0.98, RMSD 0.91 Å
- 6D6Q chain B against the predicted model Q9NPD3: TM-score 0.98, RMSD 0.91 Å
- 6D6Q chain B against the predicted model Q9NPD3: TM-score 0.98, RMSD 0.91 Å
- 9G8N chain L against the predicted model Q9NPD3: TM-score 0.97, RMSD 1.10 Å
- 6H25 chain B against the predicted model Q9NPD3: TM-score 0.97, RMSD 1.20 Å
- 6H25 chain B against the predicted model Q9NPD3: TM-score 0.97, RMSD 1.20 Å
- 9G8O chain N against the predicted model Q9NPD3: TM-score 0.97, RMSD 1.14 Å
- 2NN6 chain B against the predicted model Q9NPD3: TM-score 0.96, RMSD 1.25 Å
- 2NN6 chain B against the predicted model Q9NPD3: TM-score 0.96, RMSD 1.25 Å
Elsewhere
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