UniProt Q9M1A8
DNA-directed RNA polymerases II, IV and V subunit 8B (Q9M1A8)
DNA-directed RNA polymerases II, IV and V subunit 8B (UniProt Q9M1A8): 8 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9M1A8
- Protein
- DNA-directed RNA polymerases II, IV and V subunit 8B
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 10 · 6 records with a druggable one
Structures
9 records of Q9M1A8 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EU0 | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | electron microscopy | H | — | 1 (best 0.76) |
| 7EU0 | The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex | electron microscopy | H | — | — |
| 7EU1 | The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme | electron microscopy | H | — | 1 (best 0.77) |
| 7EU1 | The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme | electron microscopy | H | — | — |
| 8XMB | NTP-bound Pol IV transcription elongation complex | electron microscopy | H | — | 2 (best 0.79) |
| 8XMC | Post-translocated Pol IV transcription elongation complex | electron microscopy | H | — | 1 (best 0.75) |
| 8XMD | Pre-translocated Pol IV transcription elongation complex | electron microscopy | H | — | 2 (best 0.79) |
| 8XME | Backtracked Pol IV transcription elongation complex | electron microscopy | H | — | 2 (best 0.79) |
| Q9M1A8 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 8B (Q9M1A8) | predicted | A | — | 1 (best 0.39) |
Experiment against prediction
- 8XMC chain H against the predicted model Q9M1A8: TM-score 0.92, RMSD 1.44 Å
- 7EU0 chain H against the predicted model Q9M1A8: TM-score 0.92, RMSD 1.53 Å
- 7EU0 chain H against the predicted model Q9M1A8: TM-score 0.92, RMSD 1.53 Å
- 8XMD chain H against the predicted model Q9M1A8: TM-score 0.92, RMSD 1.47 Å
- 8XME chain H against the predicted model Q9M1A8: TM-score 0.92, RMSD 1.48 Å
- 8XMB chain H against the predicted model Q9M1A8: TM-score 0.91, RMSD 1.52 Å
- 7EU1 chain H against the predicted model Q9M1A8: TM-score 0.88, RMSD 1.80 Å
- 7EU1 chain H against the predicted model Q9M1A8: TM-score 0.88, RMSD 1.80 Å
Elsewhere
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