UniProt Q9KHV6
Type-2 restriction enzyme AgeI (Q9KHV6)
Type-2 restriction enzyme AgeI (UniProt Q9KHV6), EC 3.1.21.4: 6 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9KHV6
- Protein
- Type-2 restriction enzyme AgeI
- EC
- 3.1.21.4
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 16 · 4 records with a druggable one
Structures
7 records of Q9KHV6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DWA | Crystal structure of pre-specific restriction endonuclease AgeI-DNA complex | x-ray diffraction | A, B | — | 8 (best 0.74) |
| 5DWA | Crystal structure of pre-specific restriction endonuclease agei-DNA complex | x-ray diffraction | A, B | — | — |
| 5DWB | Crystal structure of specific restriction endonuclease AgeI-DNA complex | x-ray diffraction | A, B | — | 5 (best 0.64) |
| 5DWB | Crystal structure of specific restriction endonuclease agei-DNA complex | x-ray diffraction | A, B | — | — |
| 5DWC | Crystal structure of restriction endonuclease AgeI | x-ray diffraction | A | — | 2 (best 0.56) |
| 5DWC | Crystal structure of restriction endonuclease agei | x-ray diffraction | A | — | — |
| Q9KHV6 | AlphaFold monomer V2.0 prediction for type-2 restriction enzyme agei (Q9KHV6) | predicted | A | — | 1 (best 0.55) |
Experiment against prediction
- 5DWB chain A against the predicted model Q9KHV6: TM-score 0.98, RMSD 0.82 Å
- 5DWB chain A against the predicted model Q9KHV6: TM-score 0.98, RMSD 0.82 Å
- 5DWA chain A against the predicted model Q9KHV6: TM-score 0.98, RMSD 1.01 Å
- 5DWA chain A against the predicted model Q9KHV6: TM-score 0.98, RMSD 1.01 Å
- 5DWC chain A against the predicted model Q9KHV6: TM-score 0.97, RMSD 1.33 Å
- 5DWC chain A against the predicted model Q9KHV6: TM-score 0.97, RMSD 1.33 Å
Elsewhere
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