UniProt Q9JZW6
3-methyl-2-oxobutanoate hydroxymethyltransferase (Q9JZW6)
3-methyl-2-oxobutanoate hydroxymethyltransferase (UniProt Q9JZW6): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9JZW6
- Protein
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of Q9JZW6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1O66 | Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase | x-ray diffraction | A, B, C, D, E | — | — |
| 1O66 | Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase | x-ray diffraction | A, B, C, D, E | — | — |
| 1O68 | Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase | x-ray diffraction | A, B, C, D, E | — | — |
| 1O68 | Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase | x-ray diffraction | A, B, C, D, E | — | — |
| Q9JZW6 | AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q9JZW6) | predicted | A | — | 2 (best 0.66) |
Experiment against prediction
- 1O66 chain D against the predicted model Q9JZW6: TM-score 1.00, RMSD 0.24 Å
- 1O66 chain D against the predicted model Q9JZW6: TM-score 1.00, RMSD 0.24 Å
- 1O68 chain A against the predicted model Q9JZW6: TM-score 1.00, RMSD 0.29 Å
- 1O68 chain A against the predicted model Q9JZW6: TM-score 1.00, RMSD 0.29 Å
- 1O66 chain A against the predicted model Q9JZW6: TM-score 1.00, RMSD 0.34 Å
- 1O66 chain A against the predicted model Q9JZW6: TM-score 1.00, RMSD 0.34 Å
- 1O68 chain E against the predicted model Q9JZW6: TM-score 0.99, RMSD 0.23 Å
- 1O68 chain E against the predicted model Q9JZW6: TM-score 0.99, RMSD 0.23 Å
- 1O68 chain B against the predicted model Q9JZW6: TM-score 0.99, RMSD 0.26 Å
- 1O68 chain B against the predicted model Q9JZW6: TM-score 0.99, RMSD 0.26 Å
Elsewhere
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