UniProt Q9JMA2

Queuine tRNA-ribosyltransferase catalytic subunit 1 (Q9JMA2)

Queuine tRNA-ribosyltransferase catalytic subunit 1 (UniProt Q9JMA2), EC 2.4.2.29: 11 experimental structures on GenesisL1, 5 ligands bound, 44 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: Q9JMA2
Protein: Queuine tRNA-ribosyltransferase catalytic subunit 1
EC: 2.4.2.29
Experimental structures: 11
Predicted models: 0
Ligands: 5
Pockets: 44 · 5 records with a druggable one

Structures

11 records of Q9JMA2 in the MolNFT archive: 11 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6H62	QTRT1, the catalytic subunit of murine tRNA-Guanine Transglycosylase	x-ray diffraction	A, B	ZN	9 (best 0.73)
6H62	QTRT1, the catalytic subunit of murine tRNA-guanine transglycosylase	x-ray diffraction	A, B	ZN	—
7B2I	Heterodimeric tRNA-guanine transglycosylase from mouse	x-ray diffraction	C	SO4, ZN	—
7OV9	Heterodimeric tRNA-Guanine Transglycosylase from mouse, apo-structure	x-ray diffraction	C	SO4, ZN	13 (best 0.72)
7OV9	Heterodimeric tRNA-guanine transglycosylase from mouse, apo-structure	x-ray diffraction	C	SO4, ZN	—
7OVO	Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine	x-ray diffraction	C	SO4, QEI, ZN	9 (best 0.69)
7OVO	Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine	x-ray diffraction	C	SO4, QEI, ZN	—
7OVS	Heterodimeric murine tRNA-guanine transglycosylase in the presence of Anderson-Evans type (TEW) and…	x-ray diffraction	C	ZN, 2I2, TEW	7 (best 0.59)
7OVS	Heterodimeric murine tRNA-guanine transglycosylase in the presence of anderson-evans type (tew) and…	x-ray diffraction	C	ZN, 2I2, TEW	—
7OWZ	Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine and in the presence of…	x-ray diffraction	C	ZN, QEI, 2I2	6 (best 0.59)
Q9JMA2	AlphaFold monomer V2.0 prediction for queuine tRNA-ribosyltransferase catalytic subunit 1 (Q9JMA2)	—		—	—

Ligands

ZN · Zinc ion · in 10 records
SO4 · Sulfate ion · in 5 records
2I2 · pentadecaoxodiphosphopentatungstate · in 3 records
QEI · 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one · in 3 records
TEW · 6-tungstotellurate(VI) · in 2 records

Elsewhere

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