UniProt Q9JI92
Syntenin-1 (Q9JI92)
Syntenin-1 (UniProt Q9JI92): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9JI92
- Protein
- Syntenin-1
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
10 records of Q9JI92 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5A2P | The complex structure of PDZ domains in syntenin-1 with 4L peptide | x-ray diffraction | A, B, C, D | — | — |
| 5A2P | The complex structure of PDZ domains in syntenin-1 with 4L peptide | x-ray diffraction | A, B, C, D | — | — |
| 5G1D | The complex structure of syntenin-1 PDZ domain with c-terminal extension | x-ray diffraction | A, B | — | — |
| 5G1D | The complex structure of syntenin-1 PDZ domain with C-terminal extension | x-ray diffraction | A, B | — | — |
| 5G1E | The complex structure of syntenin-1 PDZ domain with c-terminal extension | x-ray diffraction | A, B | — | — |
| 5G1E | The complex structure of syntenin-1 PDZ domain with C-terminal extension | x-ray diffraction | A, B | — | — |
| 6AK2 | Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 | x-ray diffraction | A, B | — | — |
| 6AK2 | Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor ksl-128018 | x-ray diffraction | A, B | — | — |
| 8HU2 | Rattus Syntenin-1 PDZ domain with inhibitor | x-ray diffraction | A | M8R | 2 (best 0.35) |
| Q9JI92 | AlphaFold monomer V2.0 prediction for syntenin-1 (Q9JI92) | predicted | A | — | 5 (best 0.58) |
Ligands
- M8R · (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid · in 1 record
Experiment against prediction
- 5G1E chain A against the predicted model Q9JI92: TM-score 0.99, RMSD 0.59 Å
- 5G1E chain A against the predicted model Q9JI92: TM-score 0.99, RMSD 0.59 Å
- 5G1E chain B against the predicted model Q9JI92: TM-score 0.99, RMSD 0.58 Å
- 5G1E chain B against the predicted model Q9JI92: TM-score 0.99, RMSD 0.58 Å
- 5G1D chain A against the predicted model Q9JI92: TM-score 0.96, RMSD 0.95 Å
- 5G1D chain A against the predicted model Q9JI92: TM-score 0.96, RMSD 0.95 Å
- 5G1D chain B against the predicted model Q9JI92: TM-score 0.96, RMSD 0.97 Å
- 5G1D chain B against the predicted model Q9JI92: TM-score 0.96, RMSD 0.97 Å
- 5A2P chain A against the predicted model Q9JI92: TM-score 0.91, RMSD 1.57 Å
- 5A2P chain A against the predicted model Q9JI92: TM-score 0.91, RMSD 1.57 Å
Elsewhere
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