UniProt Q9HZK0
Beta-hexosaminidase (Q9HZK0)
Beta-hexosaminidase (UniProt Q9HZK0), EC 3.2.1.52: 13 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9HZK0
- Protein
- Beta-hexosaminidase
- EC
- 3.2.1.52
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 14 · 3 records with a druggable one
Structures
14 records of Q9HZK0 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5G1M | Crystal structure of NagZ from Pseudomonas aeruginosa | x-ray diffraction | A, B | CL | — |
| 5G1M | Crystal structure of nagz from pseudomonas aeruginosa | x-ray diffraction | A, B | — | — |
| 5G2M | Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine | x-ray diffraction | A, B | NAG | — |
| 5G2M | Crystal structure of nagz from pseudomonas aeruginosa in complex with N-acetylglucosamine | x-ray diffraction | A, B | — | — |
| 5G3R | Crystal structure of nagz from pseudomonas aeruginosa in complex with N-acetylglucosamine and… | x-ray diffraction | A, B | — | — |
| 5G5K | Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor… | x-ray diffraction | A, B | NOK | 4 (best 0.73) |
| 5G5K | Crystal structure of nagz from pseudomonas aeruginosa in complex with the inhibitor… | x-ray diffraction | A, B | — | — |
| 5G5U | Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa | x-ray diffraction | A, B | — | — |
| 5G5U | Crystal structure of nagz H174A mutant from pseudomonas aeruginosa | x-ray diffraction | A, B | — | — |
| 5G6T | Crystal structure of Zn-containing NagZ H174A mutant from Pseudomonas aeruginosa | x-ray diffraction | A, B | ZN | 8 (best 0.78) |
| 5G6T | Crystal structure of zn-containing nagz H174A mutant from pseudomonas aeruginosa | x-ray diffraction | A, B | — | — |
| 5LY7 | Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor… | x-ray diffraction | A, B | NOK | — |
| 5LY7 | Crystal structure of nagz H174A mutant from pseudomonas aeruginosa in complex with the inhibitor… | x-ray diffraction | A, B | NOK | — |
| Q9HZK0 | AlphaFold monomer V2.0 prediction for beta-hexosaminidase (Q9HZK0) | predicted | A | — | 2 (best 0.60) |
Ligands
Experiment against prediction
- 5LY7 chain A against the predicted model Q9HZK0: TM-score 0.99, RMSD 0.64 Å
- 5LY7 chain A against the predicted model Q9HZK0: TM-score 0.99, RMSD 0.64 Å
- 5G3R chain B against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.91 Å
- 5G3R chain A against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.94 Å
- 5G5K chain A against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.87 Å
- 5G5K chain A against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.87 Å
- 5G2M chain B against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.88 Å
- 5G2M chain B against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.88 Å
- 5G5K chain B against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.95 Å
- 5G5K chain B against the predicted model Q9HZK0: TM-score 0.98, RMSD 0.95 Å
Elsewhere
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