UniProt Q9HJN6
tRNA (cytidine(56)-2'-O)-methyltransferase (Q9HJN6)
tRNA (cytidine(56)-2'-O)-methyltransferase (UniProt Q9HJN6), EC 2.1.1.206: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9HJN6
- Protein
- tRNA (cytidine(56)-2'-O)-methyltransferase
- EC
- 2.1.1.206
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 3 records with a druggable one
Structures
3 records of Q9HJN6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8X6J | The X-ray structure of N-terminal catalytic domain of Thermoplasma acidophilum tRNA… | x-ray diffraction | A | SAM | 1 (best 0.58) |
| 8X6K | The X-ray structure of N-terminal catalytic domain of Thermoplasma acidophilum tRNA… | x-ray diffraction | A, B | — | 4 (best 0.63) |
| Q9HJN6 | AlphaFold monomer V2.0 prediction for tRNA (CYTIDINE(56)-2'-O)-methyltransferase (Q9HJN6) | predicted | A | — | 3 (best 0.54) |
Ligands
- SAM · S-adenosylmethionine · in 1 record
Experiment against prediction
- 8X6J chain A against the predicted model Q9HJN6: TM-score 0.99, RMSD 0.48 Å
- 8X6K chain A against the predicted model Q9HJN6: TM-score 0.99, RMSD 0.52 Å
- 8X6K chain B against the predicted model Q9HJN6: TM-score 0.97, RMSD 1.05 Å
Elsewhere
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