UniProt Q9HD40
O-phosphoseryl-tRNA(Sec) selenium transferase (Q9HD40)
O-phosphoseryl-tRNA(Sec) selenium transferase (UniProt Q9HD40), EC 2.9.1.2: 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9HD40
- Protein
- O-phosphoseryl-tRNA(Sec) selenium transferase
- EC
- 2.9.1.2
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 2 records with a druggable one
Structures
11 records of Q9HD40 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3HL2 | The crystal structure of the human SepSecS-tRNASec complex | x-ray diffraction | A, B, C, D | — | — |
| 3HL2 | The crystal structure of the human sepsecs-trnasec complex | x-ray diffraction | A, B, C, D | — | — |
| 4ZDL | The crystal structure of the T325S mutant of the human holo SepSecS | x-ray diffraction | A, B | PLR | 4 (best 0.58) |
| 4ZDL | The crystal structure of the T325S mutant of the human holo sepsecs | x-ray diffraction | A, B | — | — |
| 4ZDO | The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec) | x-ray diffraction | A, B, C, D | — | — |
| 4ZDO | The crystal structure of T325S mutant of human sepsecs in complex with selenocysteine tRNA (trnasec) | x-ray diffraction | A, B, C, D | — | — |
| 4ZDP | The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec) | x-ray diffraction | A, B, C, D | — | — |
| 4ZDP | The crystal structure of Y334C mutant of human sepsecs in complex with selenocysteine tRNA (trnasec) | x-ray diffraction | A, B, C, D | — | — |
| 7L1T | Crystal structure of human holo sepsecs | x-ray diffraction | A | PLR, PO4 | — |
| 8G9Z | High-resolution crystal structure of the human selenomethionine-derived SepSecS-tRNASec complex | x-ray diffraction | A, B, C, D | PLR | — |
| Q9HD40 | AlphaFold monomer V2.0 prediction for O-phosphoseryl-TRNA(SEC) selenium transferase (Q9HD40) | predicted | A | — | 5 (best 0.51) |
Ligands
Experiment against prediction
- 4ZDL chain A against the predicted model Q9HD40: TM-score 1.00, RMSD 0.61 Å
- 4ZDL chain A against the predicted model Q9HD40: TM-score 1.00, RMSD 0.61 Å
- 7L1T chain A against the predicted model Q9HD40: TM-score 0.99, RMSD 0.62 Å
- 4ZDL chain B against the predicted model Q9HD40: TM-score 0.99, RMSD 0.65 Å
- 4ZDO chain A against the predicted model Q9HD40: TM-score 0.99, RMSD 0.67 Å
- 4ZDO chain A against the predicted model Q9HD40: TM-score 0.99, RMSD 0.67 Å
- 4ZDO chain C against the predicted model Q9HD40: TM-score 0.99, RMSD 0.67 Å
- 4ZDO chain C against the predicted model Q9HD40: TM-score 0.99, RMSD 0.67 Å
- 3HL2 chain A against the predicted model Q9HD40: TM-score 0.99, RMSD 0.67 Å
- 3HL2 chain A against the predicted model Q9HD40: TM-score 0.99, RMSD 0.67 Å
Elsewhere
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