UniProt Q9HC77

Centromere protein J (Q9HC77)

Centromere protein J (UniProt Q9HC77): 6 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9HC77
Protein: Centromere protein J
Experimental structures: 6
Predicted models: 1
Pockets: 7 · 1 record with a druggable one

Structures

7 records of Q9HC77 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5EIB	Crystal structure of CPAP PN2-3 C-terminal loop-helix in complex with DARPin-tubulin	x-ray diffraction	F	—	3 (best 0.41)
5EIB	Crystal structure of cpap PN2-3 C-terminal loop-helix in complex with darpin-tubulin	x-ray diffraction	F	—	—
5ITZ	Crystal structure of the SAC domain of CPAP in a complex with Tubulin and Darpin	x-ray diffraction	D	—	—
5ITZ	Crystal structure of the sac domain of cpap in a complex with tubulin and darpin	x-ray diffraction	D	—	—
7Q1E	CPAP:TUBULIN:IIH5 alpharep complex	x-ray diffraction	P	—	—
7Z0G	CPAP:TUBULIN:IE5 alpharep complex P1 space group	x-ray diffraction	P, U	—	4 (best 0.83)
Q9HC77	AlphaFold monomer V2.0 prediction for centromere protein J (Q9HC77)	predicted	A	—	—

Experiment against prediction

7Q1E chain P against the predicted model Q9HC77: TM-score 0.51, RMSD 2.19 Å
7Z0G chain P against the predicted model Q9HC77: TM-score 0.45, RMSD 2.36 Å
7Z0G chain U against the predicted model Q9HC77: TM-score 0.40, RMSD 2.11 Å
5EIB chain F against the predicted model Q9HC77: TM-score 0.32, RMSD 1.69 Å
5EIB chain F against the predicted model Q9HC77: TM-score 0.32, RMSD 1.69 Å
5ITZ chain D against the predicted model Q9HC77: TM-score 0.30, RMSD 1.33 Å
5ITZ chain D against the predicted model Q9HC77: TM-score 0.30, RMSD 1.33 Å

Elsewhere

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