UniProt Q9HBE4
Interleukin-21 (Q9HBE4)
Interleukin-21 (UniProt Q9HBE4): 5 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9HBE4
- Protein
- Interleukin-21
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 14 · 1 record with a druggable one
Structures
6 records of Q9HBE4 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OQP | Solution structure of human interleukin-21 | solution nmr | A | — | — |
| 2OQP | Solution structure of human interleukin-21 | solution nmr | A | — | — |
| 3TGX | IL-21:IL21R complex | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 3TGX | Il-21:IL21R complex | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 8ENT | Interleukin-21 signaling complex with IL-21R and IL-2Rg | x-ray diffraction | A, D, G, J | — | 14 (best 0.65) |
| Q9HBE4 | AlphaFold monomer V2.0 prediction for interleukin-21 (Q9HBE4) | predicted | A | — | — |
Experiment against prediction
- 3TGX chain P against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.72 Å
- 3TGX chain P against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.72 Å
- 3TGX chain N against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.73 Å
- 3TGX chain N against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.73 Å
- 3TGX chain L against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.93 Å
- 3TGX chain L against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.93 Å
- 3TGX chain F against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.83 Å
- 3TGX chain F against the predicted model Q9HBE4: TM-score 0.97, RMSD 0.83 Å
- 3TGX chain J against the predicted model Q9HBE4: TM-score 0.96, RMSD 0.93 Å
- 3TGX chain J against the predicted model Q9HBE4: TM-score 0.96, RMSD 0.93 Å
Elsewhere
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