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UniProt Q9HAZ1

Dual specificity protein kinase CLK4 (Q9HAZ1)

Dual specificity protein kinase CLK4 (UniProt Q9HAZ1), EC 2.7.12.1: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
Q9HAZ1
Protein
Dual specificity protein kinase CLK4
EC
2.7.12.1
Experimental structures
2
Predicted models
1
Ligands
2
Pockets
1 · 1 record with a druggable one

Structures

3 records of Q9HAZ1 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6FYVX-ray structure of CLK4-KD(146-480)/CX-4945 at 2.46Ax-ray diffractionA3NG, SO41 (best 0.67)
6FYVX-ray structure of CLK4-KD(146-480)/CX-4945 at 2.46Ax-ray diffractionA3NG, SO4—
Q9HAZ1AlphaFold monomer V2.0 prediction for dual specificity protein kinase CLK4 (Q9HAZ1)predictedA——

Ligands

  • 3NG · 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid · in 2 records
  • SO4 · Sulfate ion · in 2 records

Experiment against prediction

Elsewhere

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