UniProt Q9HAB8
Phosphopantothenate--cysteine ligase (Q9HAB8)
Phosphopantothenate--cysteine ligase (UniProt Q9HAB8), EC 6.3.2.51: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9HAB8
- Protein
- Phosphopantothenate--cysteine ligase
- EC
- 6.3.2.51
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 16 · 2 records with a druggable one
Structures
5 records of Q9HAB8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1P9O | Crystal Structure of Phosphopantothenoylcysteine Synthetase | x-ray diffraction | A, B | — | — |
| 1P9O | Crystal structure of phosphopantothenoylcysteine synthetase | x-ray diffraction | A, B | — | — |
| 7EDZ | Crystal Structure of human PPCS in complex with P-HoPan and AMPPNP | x-ray diffraction | D, C, B, A | ANP, SO4, MG, J1O | 12 (best 0.82) |
| 7EDZ | Crystal structure of human ppcs in complex with P-hopan and amppnp | x-ray diffraction | D, C, B, A | ANP, SO4, MG, J1O | — |
| Q9HAB8 | AlphaFold monomer V2.0 prediction for phosphopantothenate--cysteine ligase (Q9HAB8) | predicted | A | — | 4 (best 0.71) |
Ligands
Experiment against prediction
- 7EDZ chain D against the predicted model Q9HAB8: TM-score 0.98, RMSD 1.06 Å
- 7EDZ chain D against the predicted model Q9HAB8: TM-score 0.98, RMSD 1.06 Å
- 7EDZ chain C against the predicted model Q9HAB8: TM-score 0.98, RMSD 1.08 Å
- 7EDZ chain C against the predicted model Q9HAB8: TM-score 0.98, RMSD 1.08 Å
- 7EDZ chain B against the predicted model Q9HAB8: TM-score 0.98, RMSD 1.08 Å
- 7EDZ chain B against the predicted model Q9HAB8: TM-score 0.98, RMSD 1.08 Å
- 1P9O chain A against the predicted model Q9HAB8: TM-score 0.96, RMSD 1.22 Å
- 1P9O chain A against the predicted model Q9HAB8: TM-score 0.96, RMSD 1.22 Å
- 1P9O chain B against the predicted model Q9HAB8: TM-score 0.96, RMSD 1.30 Å
- 1P9O chain B against the predicted model Q9HAB8: TM-score 0.96, RMSD 1.30 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.