UniProt Q9H9Q2
COP9 signalosome complex subunit 7b (Q9H9Q2)
COP9 signalosome complex subunit 7b (UniProt Q9H9Q2): 11 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H9Q2
- Protein
- COP9 signalosome complex subunit 7b
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 15 · 7 records with a druggable one
Structures
12 records of Q9H9Q2 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6R6H | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | 3 (best 0.81) |
| 6R6H | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | — |
| 6R7F | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | 3 (best 0.81) |
| 6R7F | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | — |
| 6R7H | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | 2 (best 0.86) |
| 6R7H | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | — |
| 6R7I | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | 3 (best 0.87) |
| 6R7I | Structural basis of cullin-2 ring E3 ligase regulation by the COP9 signalosome | electron microscopy | G | — | — |
| 8H38 | Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex | electron microscopy | G | — | 2 (best 0.77) |
| 8H3A | Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex | electron microscopy | G | — | 1 (best 0.70) |
| 8H3F | Cryo-EM Structure of the KBTBD2-CRL3-CSN complex | electron microscopy | G | — | 1 (best 0.75) |
| Q9H9Q2 | AlphaFold monomer V2.0 prediction for COP9 signalosome complex subunit 7B (Q9H9Q2) | predicted | A | — | — |
Experiment against prediction
- 6R7F chain G against the predicted model Q9H9Q2: TM-score 0.92, RMSD 1.65 Å
- 6R7F chain G against the predicted model Q9H9Q2: TM-score 0.92, RMSD 1.65 Å
- 8H38 chain G against the predicted model Q9H9Q2: TM-score 0.89, RMSD 2.18 Å
- 8H3F chain G against the predicted model Q9H9Q2: TM-score 0.86, RMSD 2.27 Å
- 8H3A chain G against the predicted model Q9H9Q2: TM-score 0.86, RMSD 2.40 Å
- 6R7H chain G against the predicted model Q9H9Q2: TM-score 0.84, RMSD 2.51 Å
- 6R7H chain G against the predicted model Q9H9Q2: TM-score 0.84, RMSD 2.51 Å
- 6R7I chain G against the predicted model Q9H9Q2: TM-score 0.83, RMSD 2.54 Å
- 6R7I chain G against the predicted model Q9H9Q2: TM-score 0.83, RMSD 2.54 Å
- 6R6H chain G against the predicted model Q9H9Q2: TM-score 0.83, RMSD 2.74 Å
Elsewhere
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