UniProt Q9H8M5
Metal transporter CNNM2 (Q9H8M5)
Metal transporter CNNM2 (UniProt Q9H8M5): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H8M5
- Protein
- Metal transporter CNNM2
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 1 record with a druggable one
Structures
14 records of Q9H8M5 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IY0 | Structural and ligand binding properties of the Bateman domain of human magnesium transporters… | x-ray diffraction | A | — | — |
| 4IY0 | Structural and ligand binding properties of the bateman domain of human magnesium transporters… | x-ray diffraction | A | — | — |
| 4IY2 | Structural and ligand binding properties of the Bateman domain of human magnesium transporters… | x-ray diffraction | A, C | — | — |
| 4IY2 | Structural and ligand binding properties of the bateman domain of human magnesium transporters… | x-ray diffraction | A, C | — | — |
| 4IY4 | Structural and ligand binding properties of the Bateman domain of human magnesium transporters… | x-ray diffraction | A, C | — | — |
| 4IY4 | Structural and ligand binding properties of the bateman domain of human magnesium transporters… | x-ray diffraction | A, C | — | — |
| 4IYS | Structural and ligand binding properties of the Bateman domain of human magnesium transporters… | x-ray diffraction | A | — | — |
| 4IYS | Structural and ligand binding properties of the bateman domain of human magnesium transporters… | x-ray diffraction | A | — | — |
| 6DJ3 | Crystal structure of CNNM2 cyclic nucleotide-binding homology domain | x-ray diffraction | A, B | — | 2 (best 0.35) |
| 6DJ3 | Crystal structure of CNNM2 cyclic nucleotide-binding homology domain | x-ray diffraction | A, B | — | — |
| 6N7E | Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-PNP and Mg2+ | x-ray diffraction | A, B, C, D | ANP, MG | — |
| 6N7E | Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-pnp and MG2+ | x-ray diffraction | A, B, C, D | ANP, MG | — |
| 8F6D | Crystal structure of the CNNM2 CBS-pair domain in complex with ARL15 | x-ray diffraction | A, C, E, G | — | 13 (best 0.82) |
| Q9H8M5 | AlphaFold monomer V2.0 prediction for metal transporter CNNM2 (Q9H8M5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6DJ3 chain A against the predicted model Q9H8M5: TM-score 0.97, RMSD 1.00 Å
- 6DJ3 chain A against the predicted model Q9H8M5: TM-score 0.97, RMSD 1.00 Å
- 4IY4 chain A against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.85 Å
- 4IY4 chain A against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.85 Å
- 4IY0 chain A against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.84 Å
- 4IY0 chain A against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.84 Å
- 4IY4 chain C against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.85 Å
- 4IY4 chain C against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.85 Å
- 4IY2 chain C against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.83 Å
- 4IY2 chain C against the predicted model Q9H8M5: TM-score 0.97, RMSD 0.83 Å
Elsewhere
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