UniProt Q9H5U6
rRNA N6-adenosine-methyltransferase ZCCHC4 (Q9H5U6)
rRNA N6-adenosine-methyltransferase ZCCHC4 (UniProt Q9H5U6), EC 2.1.1.-: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9H5U6
- Protein
- rRNA N6-adenosine-methyltransferase ZCCHC4
- EC
- 2.1.1.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 28 · 2 records with a druggable one
Structures
3 records of Q9H5U6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6UCA | Crystal structure of human ZCCHC4 in complex with SAH | x-ray diffraction | A, B, C, D, E, F | SAH, ZN | 20 (best 0.78) |
| 6UCA | Crystal structure of human ZCCHC4 in complex with sah | x-ray diffraction | A, B, C, D, E, F | ZN | — |
| Q9H5U6 | AlphaFold monomer V2.0 prediction for rRNA N6-adenosine- methyltransferase ZCCHC4 (Q9H5U6) | predicted | A | — | 8 (best 0.71) |
Ligands
Experiment against prediction
- 6UCA chain E against the predicted model Q9H5U6: TM-score 0.98, RMSD 1.05 Å
- 6UCA chain F against the predicted model Q9H5U6: TM-score 0.98, RMSD 1.06 Å
- 6UCA chain B against the predicted model Q9H5U6: TM-score 0.98, RMSD 1.08 Å
- 6UCA chain E against the predicted model Q9H5U6: TM-score 0.98, RMSD 1.05 Å
- 6UCA chain F against the predicted model Q9H5U6: TM-score 0.98, RMSD 1.06 Å
- 6UCA chain B against the predicted model Q9H5U6: TM-score 0.98, RMSD 1.08 Å
- 6UCA chain A against the predicted model Q9H5U6: TM-score 0.97, RMSD 1.48 Å
- 6UCA chain C against the predicted model Q9H5U6: TM-score 0.97, RMSD 1.30 Å
- 6UCA chain A against the predicted model Q9H5U6: TM-score 0.97, RMSD 1.48 Å
- 6UCA chain C against the predicted model Q9H5U6: TM-score 0.97, RMSD 1.30 Å
Elsewhere
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